Evidence map›Paper›PMID 34047818›Full record

ArticleActa neuropathologica2021

Alzheimer's disease neuropathological change three decades after iatrogenic amyloid-β transmission.

Zane Jaunmuktane, Gargi Banerjee, Simon Paine, Adrian Parry-Jones, Peter Rudge, Joan Grieve, Ahmed K Toma, Simon F Farmer, Simon Mead, Henry Houlden and 2 more

Abstract readCase Reports
In one paragraph

Article in Acta neuropathologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Evidence for progressive neurodegeneration in iatrogenic cerebral amyloid angiopathy.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Iatrogenic cerebral amyloid angiopathy and Alzheimer's disease co-pathology.Annals of clinical and translational neurology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Neurodegenerative Disease Tauopathies.Annual review of pathology · 2024
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Zane JaunmuktaneDivision of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK. z.jaunmuktane@ucl.ac.uk.
Gargi BanerjeeMRC Prion Unit at UCL, Institute of Prion Diseases, University College London, London, W1W 7FF, UK.
Simon PaineNeuropathology Laboratory, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, NG7 2UH, UK.
Adrian Parry-JonesGeoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance, University of Manchester, Manchester, M13 9PL, UK.
Peter RudgeMRC Prion Unit at UCL, Institute of Prion Diseases, University College London, London, W1W 7FF, UK.
Joan GrieveVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK.
Ahmed K TomaVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK.
Simon F FarmerDepartment of Clinical and Movement Neurosciences and Queen Square Brain Bank for Neurological Disorders, Queen Square Institute of Neurology, University College London, London, WC1N 3BG, UK.
Simon MeadMRC Prion Unit at UCL, Institute of Prion Diseases, University College London, London, W1W 7FF, UK.
Henry HouldenNeurogenetics Laboratory, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK.
David J WerringDepartment of Neurology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK.
Sebastian BrandnerDivision of Neuropathology, National Hospital for Neurology and Neurosurgery, University College London NHS Foundation Trust, London, WC1N 3BG, UK. s.brandner@ucl.ac.uk.ORCID http://orcid.org/0000-0002-9821-0342

Funding

Medical Research Council G0701018Medical Research Council G1100578Medical Research Council MC_UU_00024/1Medical Research Council MR/N004272/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Iatrogenic DiseaseAdultAlzheimer DiseaseAmyloid beta-PeptidesBrain NeoplasmsCognitive DysfunctionEmbolization, TherapeuticFemaleHemangiomaHumansMaleMedulloblastomaMiddle AgedTauopathiesAmyloid beta-Peptides

Identifiers

PMID34047818
PMCPMC8217014

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.