Evidence map›Paper›PMID 34047633›Full record

ArticleApplied and environmental microbiology2021

The Yeast eIF2 Kinase Gcn2 Facilitates H

Veronica Gast, Kate Campbell, Cecilia Picazo, Martin Engqvist, Verena Siewers, Mikael Molin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied and environmental microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Biomolecules · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Impact of Hydrogen Peroxide on Protein Synthesis in Yeast.Antioxidants (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Veronica GastDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Kate CampbellDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Cecilia PicazoDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Martin EngqvistDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Verena SiewersDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Mikael MolinDepartment of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Chalmers University of Technology · SEUniversitat de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recombinant protein production is a known source of oxidative stress. However, knowledge of which reactive oxygen species are involved or the specific growth phase in which stress occurs remains lacking. Using modern, hypersensitive genetic H

Indexed as

alpha-AmylasesEndoplasmic ReticulumFeedback, PhysiologicalHydrogen PeroxideProtein BiosynthesisProtein Serine-Threonine KinasesRecombinant ProteinsSaccharomyces cerevisiaeSaccharomyces cerevisiae Proteinsalpha-AmylasesGCN2 protein, S cerevisiaeHydrogen PeroxideProtein Serine-Threonine KinasesRecombinant ProteinsSaccharomyces cerevisiae ProteinsER stressGcn4H2O2heterologous protein productionhydrogen peroxideoxidative stressprotein kinase Gcn2recombinant protein productiontranslational control

Identifiers

PMID34047633
PMCPMC8276805
OpenAlexW3165730405

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.