Evidence map›Paper›PMID 34047481›Full record

ArticleClinical and translational medicine2021

NRF2 activation induced by PML-RARα promotes microRNA 125b-1 expression and confers resistance to chemotherapy in acute promyelocytic leukemia.

Xibao Yu, Ardalan Mansouri, Zhuandi Liu, Rili Gao, Kehan Li, Cunte Chen, Youxue Huang, Zheng Chen, Shaohua Chen, Yuhong Lu and 3 more

Open access · goldAbstract readLetter
In one paragraph

Article in Clinical and translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Xibao YuDepartment of Experimental Research, Sun Yat-Sen University Cancer Center, State Key Laboratory Oncology in South China, Guangzhou, China.ORCID 0000-0003-0643-8372
Ardalan MansouriKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.
Zhuandi LiuKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.
Rili GaoKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.
Kehan LiKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.
Cunte ChenKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.
Youxue HuangKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.
Zheng ChenKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.
Shaohua ChenKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.
Yuhong LuDepartment of Hematology, First Affiliated Hospital, Jinan University, Guangzhou, China.
Yangqiu LiKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.ORCID 0000-0002-0974-4036
Chengwu ZengKey Laboratory for Regenerative Medicine of Ministry of Education, Institute of Hematology, School of Medicine, Jinan University, Guangzhou, China.ORCID 0000-0002-1333-3918
Yixin ZengDepartment of Experimental Research, Sun Yat-Sen University Cancer Center, State Key Laboratory Oncology in South China, Guangzhou, China.
Jinan University · CNSun Yat-sen University · CNFirst Affiliated Hospital of Jinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antineoplastic AgentsDrug Resistance, NeoplasmHumansLeukemia, Promyelocytic, AcuteMicroRNAsNF-E2-Related Factor 2Oncogene Proteins, FusionAntineoplastic AgentsMicroRNAsMIRN125 microRNA, humanNFE2L2 protein, humanNF-E2-Related Factor 2Oncogene Proteins, Fusionpromyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein

Identifiers

PMID34047481
PMCPMC8101532
OpenAlexW3161784062

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.