Evidence map›Paper›PMID 34047245›Full record

SynthesisExpert review of vaccines2021

Challenges targeting cancer neoantigens in 2021: a systematic literature review.

Ina Chen, Michael Y Chen, S Peter Goedegebuure, William E Gillanders

Abstract readSystematic Review
In one paragraph

Synthesis in Expert review of vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Technical review of artificial intelligence in TCR-T therapy.Journal of the National Cancer Center · 2026
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Tumor-Derived Antigenic Peptides as Potential Cancer Vaccines.International journal of molecular sciences · 2024
    Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ina ChenDepartment of Surgery, Washington University and Siteman Cancer Center in St. Louis, St Louis, Missouri, USA.
Michael Y ChenDepartment of Surgery, Washington University and Siteman Cancer Center in St. Louis, St Louis, Missouri, USA.
S Peter GoedegebuureDepartment of Surgery, Washington University and Siteman Cancer Center in St. Louis, St Louis, Missouri, USA.
William E GillandersDepartment of Surgery, Washington University and Siteman Cancer Center in St. Louis, St Louis, Missouri, USA.

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI AIMEE S JAMES · 2001 to 2026
$128.0M
SURGICAL ONCOLOGY TRAINING GRANTT32CA009621 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN, William E. Gillanders · 1988 to 2026
$12.9M
Targeting Neoantigens in Triple Negative Breast CancerR01CA240983 · NCI · WASHINGTON UNIVERSITY · PI GILLANDERS, WILLIAM E., SCHREIBER, ROBERT DAVID · 2019 to 2023
$3.2M
NCI NIH HHS P30 CA091842NCI NIH HHS R01 CA240983NCI NIH HHS T32 CA009621
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cancer VaccinesNeoplasmsAntigens, NeoplasmHumansImmunotherapyTumor MicroenvironmentAntigens, NeoplasmCancer Vaccinesbinding affinitycancer immunotherapyCancer neoantigenepitope predictionimmune checkpoint inhibitionMHC class Ineoantigen vaccinesequencing

Identifiers

PMID34047245
PMCPMC8410655

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.