Evidence map›Paper›PMID 34046997›Full record

ArticleJournal of applied clinical medical physics2021

Interfractional robustness of scanning carbon ion radiotherapy for prostate cancer: An analysis based on dose distribution from daily in-room CT images.

Keisuke Tsuchida, Shinichi Minohara, Yohsuke Kusano, Kio Kano, Wataru Anno, Yosuke Takakusagi, Nobutaka Mizoguchi, Itsuko Serizawa, Daisaku Yoshida, Koh Imura and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Keisuke TsuchidaDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Shinichi MinoharaSection of Medical Physics and Engineering, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Yohsuke KusanoSection of Medical Physics and Engineering, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Kio KanoDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Wataru AnnoDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Yosuke TakakusagiDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Nobutaka MizoguchiDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Itsuko SerizawaDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Daisaku YoshidaDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Koh ImuraSection of Medical Physics and Engineering, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Yoshiki TakayamaSection of Medical Physics and Engineering, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Tadashi KamadaDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Hiroyuki KatohDepartment of Radiation Oncology, Kanagawa Cancer Center, Yokohama, Kanagawa, Japan.
Tatsuya OhnoDepartment of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.
Kanagawa Cancer CenterKanagawa Prefectural Hospital Organization · JPGunma University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe analyzed interfractional robustness of scanning carbon ion radiotherapy (CIRT) for prostate cancer based on the dose distribution using daily in-room computed tomography (CT) images. MATERIALS AND

methodsWe analyzed 11 consecutive patients treated with scanning CIRT for localized prostate cancer in our hospital between December 2015 and January 2016. In-room CT images were taken under treatment conditions in every treatment session. The dose distribution on each in-room CT image was recalculated, while retaining the pencil beam arrangement of the initial treatment plan. Then, the dose-volume histogram (DVH) parameters including the percentage of the clinical target volume (CTV) with 95% and 90% of the prescribed dose area (V95% of CTV, V90% of CTV) and V80% of rectum were calculated. The acceptance criteria for the CTV and rectum were set at V95% of CTV ≥95%, V90% of CTV ≥98%, and V80% of rectum < 10 ml.

resultsV95% of CTV, V90% of CTV, and V80% of rectum for the reproduced plans were 98.8 ± 3.49%, 99.5 ± 2.15%, and 4.39 ± 3.96 ml, respectively. Acceptance of V95% of CTV, V90% of CTV, and V80% of rectum was obtained in 123 (94%), 125 (95%) and 117 sessions (89%), respectively. Acceptance of the mean dose of V95% of CTV, V90% of CTV, and V80% of rectum for each patient was obtained in 10 (91%), 10 (91%), and 11 patients (100%), respectively.

conclusionsWe demonstrated acceptable interfractional robustness based on the dose distribution in scanning CIRT for prostate cancer.

Indexed as

Heavy Ion RadiotherapyProstatic NeoplasmsHumansMaleRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRectumTomography, X-Ray Computedcarbon ion radiotherapyimage-guided radiotherapyin-room CTinterfractional movementprostate cancerscanning irradiation

Identifiers

PMID34046997
PMCPMC8200452
OpenAlexW3164440285

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.