Evidence map›Paper›PMID 34046808›Full record

ArticleCancer causes & control : CCC2021

A pilot study of a culturally-appropriate, educational intervention to increase participation in cancer clinical trials among African Americans and Latinos.

Jennifer Cunningham-Erves, Tilicia L Mayo-Gamble, Pamela C Hull, Tao Lu, Claudia Barajas, Caree R McAfee, Maureen Sanderson, Juan R Canedo, Katina Beard, Consuelo H Wilkins

Open access · greenAbstract read
In one paragraph

Article in Cancer causes & control : CCC, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

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  8. Understanding Inclusion and Participation of People From Black African Diaspora Communities in Health and Care Research: A Realist Review.Health expectations : an international journal of public participation in health care and health policy · 2025
    Review
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  12. Review
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  15. Intersectionality in Alzheimer's Disease: The Role of Female Sex and Black American Race in the Development and Prevalence of Alzheimer's Disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  16. Article
  17. Article
  18. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Jennifer Cunningham-ErvesDepartment of Internal Medicine, Meharry Medical College, 1005 Dr. D. B. Todd Jr. Blvd., Nashville, TN, 37208, USA. jerves@mmc.edu.ORCID http://orcid.org/0000-0002-7780-9874
Tilicia L Mayo-GambleDepartment of Health Policy and Community Health, Georgia Southern University, Statesboro, GA, USA.
Pamela C HullDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Tao LuSchool of Graduate Studies, Meharry Medical College, Nashville, TN, USA.
Claudia BarajasVanderbilt University Medical Center, Vanderbilt Ingram Cancer Center, Nashville, TN, USA.
Caree R McAfeeDivision of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
Maureen SandersonDepartment of Family and Community Medicine, Meharry Medical College, Nashville, TN, USA.
Juan R CanedoSchool of Graduate Studies, Meharry Medical College, Nashville, TN, USA.
Katina BeardMatthew Walker Community Health Center, Nashville, TN, USA.
Consuelo H WilkinsDepartment of Internal Medicine, Meharry Medical College, 1005 Dr. D. B. Todd Jr. Blvd., Nashville, TN, 37208, USA.
Meharry Medical College · USVanderbilt University Medical Center · USCommunity Health Center · USGeorgia Southern University · US

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8M
The RCMI Program in Health Disparities Research at Meharry Medical College - SupplementU54MD007586 · NIMHD · MEHARRY MEDICAL COLLEGE · PI Maureen Sanderson · 2017 to 2026
$48.2M
VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
TrainingU54CA163072 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Tuya Pal, Karen Marie Winkfield · 2011 to 2026
$20.1M
Translational Pathology CoreU54CA163069 · NCI · MEHARRY MEDICAL COLLEGE · PI ADUNYAH, SAMUEL EVANS · 2011 to 2025
$18.8M
TRAININGU54CA163066 · NCI · TENNESSEE STATE UNIVERSITY · PI MARGARET M WHALEN · 2011 to 2026
$12.8M
AHRQ HHS T32 HS026122NCATS NIH HHS UL1 TR000445NCI NIH HHS P30 CA068485NCI NIH HHS U54 CA163066NCI NIH HHS U54 CA163069NCI NIH HHS U54 CA163072NCRR NIH HHS UL1 RR024975NIH HHS P30 CA068485NIH HHS P30 CA068485-23S5NIH HHS U54 CA163066NIH HHS U54 CA163069NIH HHS U54 CA163072NIH HHS UL1 RR024975NIH HHS UL1 TR000445NIMHD NIH HHS U54 MD007586
6 · The paper itself

Abstract

aimCulturally-appropriate, educational programs are recommended to improve cancer clinical trial participation among African Americans and Latinos. This study investigated the effect of a culturally-appropriate, educational program on knowledge, trust in medical researchers, and intent for clinical trial participation among African Americans and Latinos in Middle Tennessee.

methodTrained community health educators delivered a 30-min presentation with video testimonials to 198 participants in 13 town halls. A pre-post survey design was used to evaluate the intervention among 102 participants who completed both pre- and post-surveys one to two weeks after the session.

resultsPaired-sample t-test showed significant increases in unadjusted mean scores for knowledge (p < 0.001), trust in medical researchers (p < 0.001), and willingness to participate in clinical trials (p = 0.003) after the town halls in the overall sample. After adjusting for gender and education, all three outcomes remained significant for the overall sample (knowledge: p < 0.001; trust in medical researchers: p < 0.001; willingness: p = 0.001) and for African Americans (knowledge: p < 0.001; trust in medical researchers: p = 0.007; willingness: p = 0.005). However, willingness to participate was no longer significant for Latinos (knowledge: p < 0.001; trust in medical researchers: p = 0.034; willingness: p = 0.084).

conclusionsThe culturally-appropriate, educational program showed promising results for short-term, clinical trial outcomes. Further studies should examine efficacy to improve research participation outcomes.

Indexed as

Black or African AmericanHispanic or LatinoNeoplasmsClinical Trials as TopicHealth Knowledge, Attitudes, PracticeHumansPilot ProjectsSurveys and QuestionnairesAfrican americansCancer disparitiesClinical trialsEducationLatinosPilot project

Identifiers

PMID34046808
PMCPMC8567194
OpenAlexW3159608898

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.