ArticleRice (New York, N.Y.)2021
Albino seedling lethality 4; Chloroplast 30S Ribosomal Protein S1 is Required for Chloroplast Ribosome Biogenesis and Early Chloroplast Development in Rice.
Article in Rice (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19 citing papers in PubMed, 30 citations in OpenAlex.
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- ALS2, encoding a plastid 50 S ribosomal protein L5, is essential for early chloroplast development in rice.Journal of plant research · 2026Article
- Patterns of plastid gene evolution: identifying candidate genes for plastid-nuclear incompatibility across the Campanulaceae.Frontiers in plant science · 2026Article
- Chlorophyll deficient 5 encodes a DNA helicase and is essential for chloroplast development in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Chloroplast-Localized Protein, OsAL7, with Two Elongation Factor Thermostable Domains Is Essential for Normal Chloroplast Development and Seedling Longevity inPlants (Basel, Switzerland) · 2025Article
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- Insight into the genetics of a novel white-striped leaf in rice.Frontiers in plant science · 2025Article
- RNA-Binding S1 Domain in Bacterial, Archaeal and Eukaryotic Proteins as One of the Evolutionary Markers of Symbiogenesis.International journal of molecular sciences · 2024Article
- A CRISPR/Cas9-induced male-sterile line facilitating easy hybrid production in polyploid rapeseed (Horticulture research · 2024Article
- Albino lethal 13, a chloroplast-imported protein required for chloroplast development in rice.Plant direct · 2024Article
- QTL mapping and candidate gene analysis reveal two major loci regulating green leaf color in non-heading Chinese cabbage.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- iTRAQ-based proteomic analysis reveals the effect of ribosomal proteins on essential-oil accumulation inPeerJ · 2024Article
- WLP3 Encodes the Ribosomal Protein L18 and Regulates Chloroplast Development in Rice.Rice (New York, N.Y.) · 2023Article
- Article
- Perturbation of protein homeostasis brings plastids at the crossroad between repair and dismantling.PLoS genetics · 2023Article
- Transcriptome Analysis of the Responses of Rice Leaves to Chilling and Subsequent Recovery.International journal of molecular sciences · 2022Article
- The Memory of Rice Response to Spaceflight Stress: From the Perspective of Metabolomics and Proteomics.International journal of molecular sciences · 2022Article
- The nuclear-encoded plastid ribosomal protein L18s are essential for plant development.Frontiers in plant science · 2022Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
backgroundRibosomes responsible for transcription and translation of plastid-encoded proteins in chloroplasts are essential for chloroplast development and plant growth. Although most ribosomal proteins in plastids have been identified, the molecular mechanisms regulating chloroplast biogenesis remain to be investigated.
resultsHere, we identified albinic seedling mutant albino seedling lethality 4 (asl4) caused by disruption of 30S ribosomal protein S1 that is targeted to the chloroplast. The mutant was defective in early chloroplast development and chlorophyll (Chl) biosynthesis. A 2855-bp deletion in the ASL4 allele was verified as responsible for the mutant phenotype by complementation tests. Expression analysis revealed that the ASL4 allele was highly expressed in leaf 4 sections and newly expanded leaves during early leaf development. Expression levels were increased by exposure to light following darkness. Some genes involved in chloroplast biogenesis were up-regulated and others down-regulated in asl4 mutant tissues compared to wild type. Plastid-encoded plastid RNA polymerase (PEP)-dependent photosynthesis genes and nuclear-encoded phage-type RNA polymerase (NEP)-dependent housekeeping genes were separately down-regulated and up-regulated, suggesting that plastid transcription was impaired in the mutant. Transcriptome and western blot analyses showed that levels of most plastid-encoded genes and proteins were reduced in the mutant. The decreased contents of chloroplast rRNAs and ribosomal proteins indicated that chloroplast ribosome biogenesis was impaired in the asl4 mutant.
conclusionsRice ASL4 encodes 30S ribosomal protein S1, which is targeted to the chloroplast. ASL4 is essential for chloroplast ribosome biogenesis and early chloroplast development. These data will facilitate efforts to further elucidate the molecular mechanism of chloroplast biogenesis.
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