Evidence map›Paper›PMID 34046767›Full record

ArticleJournal of molecular modeling2021

Screening and testing potential inhibitors of sulphide gas production by sulphate-reducing bacteria.

Elias Silva Dos Santos, Joalene de Azevedo Santos Ferreira, Jacson Nunes Dos Santos, Fábio Alexandre Chinalia, Josilene Lima Matos, Gustavo Coqueiro, Elias Ramos-de-Souza, Paulo Fernando de Almeida

Abstract read
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In one paragraph

Article in Journal of molecular modeling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elias Silva Dos SantosInstituto de Física, Universidade Federal da Bahia, Rua Barão de Geremoabo s/n - Ondina, Salvador, BA, 40.300-000, Brazil. eliasss@ufba.br.ORCID http://orcid.org/0000-0002-6078-0614
Joalene de Azevedo Santos FerreiraInstituto de Ciências da Saúde, Universidade Federal da Bahia, Av. Reitor Miguel Calmon, s/n - Vale do Canela, Salvador, BA, 40.231-300, Brazil.
Jacson Nunes Dos SantosInstituto de Ciências da Saúde, Universidade Federal da Bahia, Av. Reitor Miguel Calmon, s/n - Vale do Canela, Salvador, BA, 40.231-300, Brazil.
Fábio Alexandre ChinaliaInstituto de Ciências da Saúde, Universidade Federal da Bahia, Av. Reitor Miguel Calmon, s/n - Vale do Canela, Salvador, BA, 40.231-300, Brazil.
Josilene Lima MatosInstituto de Ciências da Saúde, Universidade Federal da Bahia, Av. Reitor Miguel Calmon, s/n - Vale do Canela, Salvador, BA, 40.231-300, Brazil.
Gustavo CoqueiroInstituto de Ciências da Saúde, Universidade Federal da Bahia, Av. Reitor Miguel Calmon, s/n - Vale do Canela, Salvador, BA, 40.231-300, Brazil.
Elias Ramos-de-SouzaInstituto Federal de Educação, Ciência e Tecnologia da Bahia, Rua Emídio dos Santos, s/n, Barbalho, Salvador, BA, 40.301-015, Brazil.
Paulo Fernando de AlmeidaInstituto de Ciências da Saúde, Universidade Federal da Bahia, Av. Reitor Miguel Calmon, s/n - Vale do Canela, Salvador, BA, 40.231-300, Brazil.

Funding

Consejo de Investigaciones Científicas y Tecnológicas de la Provincia de Córdoba (AR) 402822/2013-7The Brazilian Research Council CNPq DT-310475/2014-7
6 · The paper itself

Abstract

Sulphate-reducing bacteria are commonly associated with biological causes of oil well souring. Biosulphetogenesis can directly affect oil quality and storage due to the accumulation of sulphides. In addition, these microorganisms can create bio-incrustation that can clog pipes. Sulphite reductase (SIR) is the enzyme responsible for converting ion sulphite into sulphide and several substances may interfere or control such activity. This interference can hinder growth of the sulphate-reducing bacteria and, consequently, it reduces sulphide accumulation in situ. This work focuses on molecular modelling techniques along with in vitro experiments in order to investigate the potential of two essential oils and one vegetable oil as main inhibitors of sulphite reductase activity. Docking simulation identified several substances present in Rosmarinus officinalis, Tea tree and Neem extractable oils as potential inhibitors of SIR. Substances present in Neem vegetable oil are the most potent inhibitors, followed by Rosmarinus officinalis and Tea tree essential oils. The Neem oil mixture showed a superior effectiveness in intracellular SIR inhibitory effects.

Indexed as

Molecular Docking SimulationBacteriaOils, VolatileOxidoreductases Acting on Sulfur Group DonorsRosmarinusSulfatesTea Tree OilOils, VolatileOxidoreductases Acting on Sulfur Group DonorsSulfatesTea Tree OilDockingEssential oilSulphate-reducing bacteriaSulphetogenesisSulphite reductase

Identifiers

PMID34046767

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.