Evidence map›Paper›PMID 34046739›Full record

ArticleMikrochimica acta2021

Automatic and sensitive detection of West Nile virus non-structural protein 1 with a portable SERS-LFIA detector.

Xiaofei Jia, Zhenzhen Liu, Yongjin Peng, Guangzheng Hou, Wei Chen, Rui Xiao

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaofei Jia *Beijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China.
Zhenzhen Liu *Beijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China.
Yongjin PengBeijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China.
Guangzheng HouBeijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China.
Wei ChenBeijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China. chw69221@126.com.
Rui XiaoBeijing Institute of Radiation Medicine, Beijing, 100850, People's Republic of China. ruixiao203@163.com.ORCID 0000-0002-6313-4757
Academy of Military Medical Sciences · CNBeijing National Laboratory for Molecular Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A portable surface-enhanced Raman scattering (SERS)-lateral flow immunoassay (LFIA) detector has been developed for the automatic and highly sensitive detection of West Nile virus (WNV) non-structural protein 1 (NS1) and actual WNV samples. Au@Ag nanoparticles (Au@Ag NPs) labeled with double-layer Raman molecules were used as SERS tags to prepare WNV-specific SERS-LFIA strips. On this platform, the WNV-specific antigen NS1 protein was quantitatively and sensitively detected. The detection limit for the WNV NS1 protein was 0.1 ng/mL, which was 100-fold more sensitive than visual signals. The detection limit for inactivated WNV virions was 0.2 × 10

Indexed as

Antibodies, ImmobilizedGoldImmunoassayLimit of DetectionMetal NanoparticlesSilverSpectrum Analysis, RamanViral Nonstructural ProteinsWest Nile FeverWest Nile virusAntibodies, ImmobilizedGoldnonstructural protein 1, West Nile virusSilverViral Nonstructural ProteinsAutomatic detectionLateral flow immunoassayPortable detectorSurface-enhanced Raman scatteringTest strip readerWest Nile virus

Identifiers

PMID34046739
OpenAlexW3164198312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.