Evidence map›Paper›PMID 34046633›Full record

ArticleRSC medicinal chemistry2021

Novel fluorinated ring-fused chlorins as promising PDT agents against melanoma and esophagus cancer.

Nelson A M Pereira, Mafalda Laranjo, Bruno F O Nascimento, João C S Simões, João Pina, Bruna D P Costa, Gonçalo Brites, João Braz, J Sérgio Seixas de Melo, Marta Pineiro and 2 more

Abstract read
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Ring-fused chlorin-enhanced photodynamic therapy for effective cell death induction in endometrial cancer.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  4. Article
  5. Applications of Photodynamic Therapy in Endometrial Diseases.Bioengineering (Basel, Switzerland) · 2022
    Review
  6. Ring-FusedFrontiers in chemistry · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nelson A M PereiraCoimbra Chemistry Centre (CQC) and Department of Chemistry, University of Coimbra 3004-535 Coimbra Portugal tmelo@ci.uc.pt.ORCID https://orcid.org/0000-0002-1891-9010
Mafalda LaranjoInstitute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra 3000-548 Coimbra Portugal.ORCID https://orcid.org/0000-0003-0689-6007
Bruno F O NascimentoCoimbra Chemistry Centre (CQC) and Department of Chemistry, University of Coimbra 3004-535 Coimbra Portugal tmelo@ci.uc.pt.ORCID https://orcid.org/0000-0003-1532-684X
João C S SimõesCoimbra Chemistry Centre (CQC) and Department of Chemistry, University of Coimbra 3004-535 Coimbra Portugal tmelo@ci.uc.pt.ORCID https://orcid.org/0000-0001-9755-0129
João PinaCoimbra Chemistry Centre (CQC) and Department of Chemistry, University of Coimbra 3004-535 Coimbra Portugal tmelo@ci.uc.pt.ORCID https://orcid.org/0000-0003-1848-1167
Bruna D P CostaCoimbra Chemistry Centre (CQC) and Department of Chemistry, University of Coimbra 3004-535 Coimbra Portugal tmelo@ci.uc.pt.ORCID https://orcid.org/0000-0002-3995-0164
Gonçalo BritesInstitute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra 3000-548 Coimbra Portugal.ORCID https://orcid.org/0000-0003-3705-673X
João BrazCoimbra Chemistry Centre (CQC) and Department of Chemistry, University of Coimbra 3004-535 Coimbra Portugal tmelo@ci.uc.pt.ORCID https://orcid.org/0000-0003-0432-9287
J Sérgio Seixas de MeloCoimbra Chemistry Centre (CQC) and Department of Chemistry, University of Coimbra 3004-535 Coimbra Portugal tmelo@ci.uc.pt.ORCID https://orcid.org/0000-0001-9708-5079
Marta PineiroCoimbra Chemistry Centre (CQC) and Department of Chemistry, University of Coimbra 3004-535 Coimbra Portugal tmelo@ci.uc.pt.ORCID https://orcid.org/0000-0002-7460-3758
Maria Filomena BotelhoInstitute of Biophysics and Institute for Clinical and Biomedical Research (iCBR), Area of Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra 3000-548 Coimbra Portugal.ORCID https://orcid.org/0000-0001-7202-1650
Teresa M V D Pinho E MeloCoimbra Chemistry Centre (CQC) and Department of Chemistry, University of Coimbra 3004-535 Coimbra Portugal tmelo@ci.uc.pt.ORCID https://orcid.org/0000-0003-3256-4954

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Investigation of novel 4,5,6,7-tetrahydropyrazolo[1,5-

Identifiers

PMID34046633
PMCPMC8128062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.