Evidence map›Paper›PMID 34046621›Full record

ArticleRSC medicinal chemistry2021

Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice.

Baris A Borsa, Mert Sudagidan, Mehmet E Aldag, Isik I Baris, Elif E Acar, Cagatay Acuner, Murat Kavruk, Veli C Ozalp

Abstract read
In one paragraph

Article in RSC medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Baris A BorsaNucleic Acid Technologies Lab, Department of Physics, Chemistry and Biology (IFM), Linköping University SE-58183 Linköping Sweden Baris.ata.borsa@liu.se.
Mert SudagidanKit-Argem Research Centre, Konya Food and Agriculture University Meram 42080 Konya Turkey.
Mehmet E AldagDepartment of Medical Microbiology, Corlu State Hospital Tekirdag Turkey.
Isik I BarisDepartment of Pathology, Cakmak Erdem Hospital Istanbul Turkey.
Elif E AcarKit-Argem Research Centre, Konya Food and Agriculture University Meram 42080 Konya Turkey.
Cagatay AcunerDepartment of Medical Microbiology, Medical School, Yeditepe University Istanbul Turkey.
Murat KavrukTest and Calibration Center, Turkish Standards Institution (TSE) 41400, Gebze Kocaeli Turkey.
Veli C OzalpDepartment of Medical Biology, Medical School, Atilim University Incek 06830 Ankara Turkey Cengiz.ozalp@atilim.edu.tr.ORCID https://orcid.org/0000-0002-7659-5990

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic therapy comes with disturbances on human microbiota, resulting in changes of bacterial communities and thus leading to well-established health problems. In this study, we demonstrated that targeted teicoplanin administration maintains the faecal microbiota composition undisturbed in a mouse model while reaching therapeutic improvements for

Identifiers

PMID34046621
PMCPMC8130601

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.