Evidence map›Paper›PMID 34046497›Full record

ArticleBioMed research international2021

Hafiz Ishfaq Ahmad, Gulnaz Afzal, Adil Jamal, Shumaila Kiran, Musarrat Abbas Khan, Khalid Mehmood, Zahid Kamran, Irfan Ahmed, Shakeel Ahmad, Asmar Ahmad and 2 more

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

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  2. Retracted:BioMed research international · 2024
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4 · The record

Corrections and comments

  • Retraction · 2024-03-20Computer-Aided Content or Computer-Generated Content · Concerns/Issues about Data · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Results and/or Conclusions · Concerns/Issues about Peer Review · Investigation by Journal/Publisher · Investigation by Third Party · Paper Mill · Unreliable Results and/or Conclusions ·
  • Retracted
5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Hafiz Ishfaq AhmadDepartment of Animal Breeding and Genetics, University of Veterinary and Animal Sciences, Lahore, Pakistan.ORCID https://orcid.org/0000-0002-9206-2596
Gulnaz AfzalDepartment of Zoology, The Islamia University, Bahawalpur, Pakistan.
Adil JamalSciences and Research, College of Nursing, Umm Al Qura University, Makkah, 715, Saudi Arabia.
Shumaila KiranDepartment of Applied Chemistry, Government College University, Faisalabad, Pakistan.
Musarrat Abbas KhanDepartment of Animal Breeding and Genetics, Faculty of Veterinary & Animal Sciences, The Islamia University of Bahawalpur, Pakistan.
Khalid MehmoodDepartment of Clinical Medicine and Surgery, Faculty of Veterinary and Animal Science, The Islamia University, Bahawalpur, Pakistan.ORCID https://orcid.org/0000-0003-4720-8792
Zahid KamranDepartment of Animal Nutrition, Faculty of Veterinary & Animal Sciences, The Islamia University of Bahawalpur, Pakistan.
Irfan AhmedDepartment of Animal Nutrition, Faculty of Veterinary & Animal Sciences, The Islamia University of Bahawalpur, Pakistan.
Shakeel AhmadDepartment of Poultry Science, Faculty of Veterinary & Animal Sciences, The Islamia University of Bahawalpur, Pakistan.
Asmar AhmadDepartment of Zoology, The Islamia University, Bahawalpur, Pakistan.
Javed HussainDepartment of Zoology, The Islamia University, Bahawalpur, Pakistan.
Sadaf AlmasDepartment of Microbiology, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Islamia University of Bahawalpur · PKUniversity of Veterinary and Animal Sciences · PKGovernment College University, Faisalabad · PKUmm al-Qura University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytochrome (CYP) enzymes catalyze the metabolic reactions of endogenous and exogenous compounds. The superfamily of enzymes is found across many organisms, regardless of type, except for plants. Information was gathered about CYP2D enzymes through protein sequences of humans and other organisms. The secondary structure was predicted using the SOPMA. The structural and functional study of human CYP2D was conducted using ProtParam, SOPMA, Predotar 1.03, SignalP, TMHMM 2.0, and ExPASy. Most animals shared five central motifs according to motif analysis results. The tertiary structure of human CYP2D, as well as other animal species, was predicted by Phyre2. Human CYP2D proteins are heavily conserved across organisms, according to the findings. This indicates that they are descended from a single ancestor. They calculate the ratio of alpha-helices to extended strands to beta sheets to random coils. Most of the enzymes are alpha-helix, but small amounts of the random coil were also found. The data were obtained to provide us with a better understanding of mammalian proteins' functions and evolutionary relationships.

Indexed as

PhylogenyAmino Acid SequenceAnimalsComputational BiologyComputer SimulationCytochrome P-450 Enzyme SystemCytochromesHumansLigandsMiceModels, MolecularProtein Conformation, alpha-HelicalProtein Interaction Domains and MotifsProteinsProtein Structure, SecondarySequence AlignmentCytochrome P-450 Enzyme SystemCytochromesLigandsProteins

Identifiers

PMID34046497
PMCPMC8128545
OpenAlexW3162182767

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.