Evidence map›Paper›PMID 34046488›Full record

ArticleERJ open research2021

Prognostic value of right atrial dilation in patients with pulmonary embolism.

Markus H Lerchbaumer, Matthias Ebner, Christian O Ritter, Laura Steimke, Nina I J Rogge, Carmen Sentler, Aaron Thielmann, Lukas Hobohm, Karsten Keller, Joachim Lotz and 6 more

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Echocardiographic evaluation of the right atrial size and function: Relevance for clinical practice.American heart journal plus : cardiology research and practice · 2023
    Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

Markus H LerchbaumerDept of Radiology, Charité - University Medicine Berlin, Berlin, Germany.
Matthias EbnerDept of Nephrology and Medical Intensive Care, Charité - University Medicine Berlin, Berlin, Germany.
Christian O RitterInstitute for Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Laura SteimkeClinic of Cardiology and Pneumology, University Medical Center Göttingen, Göttingen, Germany.
Nina I J RoggeClinic of Cardiology and Pneumology, University Medical Center Göttingen, Göttingen, Germany.
Carmen SentlerClinic of Cardiology and Pneumology, University Medical Center Göttingen, Göttingen, Germany.
Aaron ThielmannClinic of Cardiology and Pneumology, University Medical Center Göttingen, Göttingen, Germany.
Lukas HobohmCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Mainz, Germany.ORCID https://orcid.org/0000-0002-4312-0366
Karsten KellerCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Mainz, Germany.ORCID https://orcid.org/0000-0002-0820-9584
Joachim LotzInstitute for Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany.
Gerd HasenfußGerman Center for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany.ORCID https://orcid.org/0000-0002-5942-361X
Rolf WachterGerman Center for Cardiovascular Research (DZHK), partner site Göttingen, Göttingen, Germany.
Bernd HammDept of Radiology, Charité - University Medicine Berlin, Berlin, Germany.
Stavros V KonstantinidesCenter for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Mainz, Germany.ORCID https://orcid.org/0000-0001-6359-7279
Galit AviramDept of Radiology, Tel Aviv Medical Center, affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Mareike LankeitDept of Internal Medicine and Cardiology, Charité - University Medicine Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-5211-7997
Universitätsmedizin Göttingen · DECharité - Universitätsmedizin Berlin · DEJohannes Gutenberg University Mainz · DEDemocritus University of Thrace · GRTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsRight atrial (RA) dilation and stretch provide prognostic information in patients with cardiovascular diseases. We investigated the prevalence, confounding factors and prognostic relevance of RA dilation in patients with pulmonary embolism (PE).

methodsOverall, 609 PE patients were consecutively included in a prospective single-centre registry between September 2008 and August 2017. Volumetric measurements of heart chambers were performed on routine non-electrocardiographic-gated computed tomography and plasma concentrations of mid-regional pro-atrial natriuretic peptide (MR-proANP) measured on admission. An in-hospital adverse outcome was defined as PE-related death, cardiopulmonary resuscitation, mechanical ventilation or catecholamine administration.

resultsPatients with an adverse outcome (11.2%) had larger RA volumes (median 120 (interquartile range 84-152)

conclusionsRA dilation is a frequent finding in patients with PE. However, the prognostic performance of RA dilation appears inferior compared to established risk stratification markers. MR-proANP predicted an in-hospital adverse outcome, both in unselected and normotensive PE patients, integrating different prognostic relevant information from comorbidities.

Identifiers

PMID34046488
PMCPMC8141828
OpenAlexW3126945918

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.