SynthesisFrontiers in bioengineering and biotechnology2021
Use of Amniotic Membrane and Its Derived Products for Bone Regeneration: A Systematic Review.
Synthesis in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Comparison Between Human Amniotic Membrane and Biodentine as A Pulp Capping Agent-An In Vitro Tooth Culture Study.Australian endodontic journal : the journal of the Australian Society of Endodontology Inc · 2026Article
- Biologic augmentation in rotator cuff repair: current evidence and future directions.JSES reviews, reports, and techniques · 2026Review
- Expression of BMP-2, OPG, RANKL And Number of Osteoblasts After Application of Bovine Amniotic Membrane and Secretome Umbilical Cord in Wistar Rats.Nanotheranostics · 2026Article
- Review
- In vitro and in vivo assessment of a new acellular human amnion/chorion membrane device for guided bone regeneration.Scientific reports · 2025Article
- Perspectives on the use of decellularized/devitalized and lyophilized human perinatal tissues for bone repair: Advantages and remaining challenges.Materials today. Bio · 2025Article
- De-Epithelization of the Human Amniotic Membrane Using a System Involving Ozonated Water and Ultrasound.Bioengineering (Basel, Switzerland) · 2024Article
- Amniotic membrane, a novel bioscaffold in cardiac diseases: from mechanism to applications.Frontiers in bioengineering and biotechnology · 2024Review
- The use of a new grafting material (b.Bone™) for the management of severely depressed tibial plateau fractures: Preliminary report of three cases.Trauma case reports · 2023Article
- Preparation of human amniotic membrane for transplantation in different application areas.Frontiers in transplantation · 2023Review
- Review
- Gene Expression Profiles of Human Mesenchymal Stromal Cells Derived from Wharton's Jelly and Amniotic Membrane before and after Osteo-Induction Using NanoString Platform.Current issues in molecular biology · 2022Article
- Application of Perinatal Derivatives on Oncological Preclinical Models: A Review of Animal Studies.International journal of molecular sciences · 2022Review
- Review
- Human amniotic membrane application in oral surgery-AnFrontiers in bioengineering and biotechnology · 2022Article
- General consensus on multimodal functions and validation analysis of perinatal derivatives for regenerative medicine applications.Frontiers in bioengineering and biotechnology · 2022Review
- Tips and Tricks and Clinical Outcome of Cryopreserved Human Amniotic Membrane Application for the Management of Medication-Related Osteonecrosis of the Jaw (MRONJ): A Pilot Study.Frontiers in bioengineering and biotechnology · 2022Article
- Article
- Applications of Human Amniotic Membrane for Tissue Engineering.Membranes · 2021Review
- Surgical Application of Human Amniotic Membrane and Amnion-Chorion Membrane in the Oral Cavity and Efficacy Evaluation: Corollary With Ophthalmological and Wound Healing Experiences.Frontiers in bioengineering and biotechnology · 2021Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Thanks to their biological properties, amniotic membrane (AM), and its derivatives are considered as an attractive reservoir of stem cells and biological scaffolds for bone regenerative medicine. The objective of this systematic review was to assess the benefit of using AM and amniotic membrane-derived products for bone regeneration. An electronic search of the MEDLINE-Pubmed database and the Scopus database was carried out and the selection of articles was performed following PRISMA guidelines. This systematic review included 42 articles taking into consideration the studies in which AM, amniotic-derived epithelial cells (AECs), and amniotic mesenchymal stromal cells (AMSCs) show promising results for bone regeneration in animal models. Moreover, this review also presents some commercialized products derived from AM and discusses their application modalities. Finally, AM therapeutic benefit is highlighted in the reported clinical studies. This study is the first one to systematically review the therapeutic benefits of AM and amniotic membrane-derived products for bone defect healing. The AM is a promising alternative to the commercially available membranes used for guided bone regeneration. Additionally, AECs and AMSCs associated with an appropriate scaffold may also be ideal candidates for tissue engineering strategies applied to bone healing. Here, we summarized these findings and highlighted the relevance of these different products for bone regeneration.
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