Evidence map›Paper›PMID 34046325›Full record

ArticleAvicenna journal of phytomedicine

Effect of

Zoleykha Feyzollahi, Homa Mohseni Kouchesfehani, Hanieh Jalali, Delaram Eslimi-Esfahani, Abbas Sheikh Hosseini

Open access · greenAbstract read
In one paragraph

Article in Avicenna journal of phytomedicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. The effects ofResearch in pharmaceutical sciences · 2026
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  12. The methanolic extract ofAvicenna journal of phytomedicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zoleykha FeyzollahiDepartment of Animal Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran.
Homa Mohseni KouchesfehaniDepartment of Animal Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran.
Hanieh JalaliDepartment of Animal Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran.
Delaram Eslimi-EsfahaniDepartment of Animal Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran.
Abbas Sheikh HosseiniDepartment of Animal Biology, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran.
Kharazmi University · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivePolycystic ovary syndrome (PCOS) is an endocrine system disruption that affects 6-10% of women. Some studies have reported the effect of MATERIALS AND

methodsThirty-two female rats were distributed into: control, Vitagnus-treatment (365 mg/kg for 30 days), PCOS (Letrozole for 28 days) and PCOS animals treated with Vitagnus (30 days of Vitagnus after PCOS induction). At the end of the treatments, serum and ovaries were collected for analysis. Expression level of

resultsIn the PCOS group compared to control, FSH, progesterone and estradiol levels were decreased, whereas testosterone and LH levels were significantly increased. No significant changes were observed in the Vitagnus-treated animals in compare to control. However, Vitagnus treatment in the PCOS group, resulted in a raise in progesterone, estrogen and FSH levels and a reduction in the levels of testosterone and LH. Quantitative gene expression analysis showed that PCOS induction resulted in over-expression of

conclusionIn conclusion, our results indicated that Vitagnus extract inhibited downregulation of

Indexed as

HypothalamusKisspeptinsOvarian folliclesPolycystic ovarian syndromeVitex agnuscastus extract

Identifiers

PMID34046325
PMCPMC8140208
OpenAlexW3135300906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.