Evidence map›Paper›PMID 34046258›Full record

ArticlePeerJ2021

Hospital-based case control study and animal study on the relationship between nonylphenol exposure and depression.

Ya Luo, Weihong Xu, Wei Ou, Ting Wang, Changwei Yang, Songying Xie, Jie Yu, Jie Xu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ya LuoSchool of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China.
Weihong XuSchool of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China.
Wei OuDepartment of Medicopsychology, School of Management, Zunyi Medical University, Zunyi, Guizhou, PR China.
Ting WangDepartment of Nuclear Medicine, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, PR China.
Changwei YangSchool of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China.
Songying XieSchool of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China.
Jie YuSchool of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China.
Jie XuSchool of Public Health, Zunyi Medical University, Zunyi, Guizhou, PR China.
Zunyi Medical University · CNAffiliated Hospital of Zunyi Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aim of this work is to explore the association between chronic exposure to nonylphenol (NP), a representative environmental endocrine disruptor (EED), and the risk of depression and its potential mechanism.

methodsA hospital-based case control study was conducted from August to December 2018. Forty-one patients with confirmed depression and 47 healthy volunteers were recruited. In vitro, 20 rats were randomly divided into the control group (corn oil) and NP exposure group (

resultsThe depressed patient group had higher Zung Self-Rating Depression Scale (SDS) (

conclusionChronic exposure to NP at environmental doses will result in the accumulation of NP in the brain and blood, and induction of depression, which might be associated with the alterations in the expression levels of BDNF and monoamine neurotransmitters.

Indexed as

Brain-derived neuro-trophic fatorDepressionMonoamineNeurotrnsmittersNonyphenol

Identifiers

PMID34046258
PMCPMC8139269
OpenAlexW3161548628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.