Evidence map›Paper›PMID 34046192›Full record

ArticleFuture science OA2021

Basophils as a potential marker of lupus nephritis by flow cytometry.

Yanni Jiang, Jin Chen, Yi Zhao, Yi Liu, Hong Xu, Xianming Mo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future science OA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yanni JiangDepartment of Rheumatology & Immunology, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0002-7713-1696
Jin ChenDepartment of Rheumatology & Immunology, West China Hospital, Sichuan University, Chengdu, China.
Yi ZhaoDepartment of Rheumatology & Immunology, West China Hospital, Sichuan University, Chengdu, China.
Yi LiuDepartment of Rheumatology & Immunology, West China Hospital, Sichuan University, Chengdu, China.
Hong XuLaboratory of Stem Cell Biology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University & Collaborative Innovation Center for Biotherapy, Chengdu, China.
Xianming MoDepartment of Rheumatology & Immunology, West China Hospital, Sichuan University, Chengdu, China.ORCID https://orcid.org/0000-0001-9932-7457
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo establish a convenient and simple flow cytometry immunophenotyping panel to explore immune cellular alterations and potential cellular biomarkers in systemic lupus erythematosus. MATERIALS AND

methodsThis is a cross-sectional, case-control study including 60 patients with systemic lupus erythematosus and 20 sex- and age-matched healthy controls. A 14-color immunophenotyping panel was applied to detect proportions of circulating immune mononuclear cells, and comparisons between patients and healthy controls, and subgroups of patients, were performed. Correlations between cellular proportions and other parameters were investigated.

resultsAfter multivariate analysis, significantly decreased proportions of CD4

conclusionIn the present study, we found that basophil proportions may be a biomarker of LN.

Indexed as

basophilsCD4−CD8− T cellsimmunophenotypeinnate lymphoid cellslupus nephritissystemic lupus erythematosus

Identifiers

PMID34046192
PMCPMC8147755
OpenAlexW3129606248

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.