Evidence map›Paper›PMID 34046164›Full record

ReviewF1000Research2021

A review of experimental models of focal cerebral ischemia focusing on the middle cerebral artery occlusion model.

Melissa Trotman-Lucas, Claire L Gibson

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Animal stroke models and outcome evaluation: A review.Animal models and experimental medicine · 2026
    Review
  4. Review
  5. Article
  6. METTL16 Promotes Cerebral Ischemia-Reperfusion Injury via mInternational journal of general medicine · 2026
    Article
  7. Article
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  9. InOpen veterinary journal · 2025
    Article
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  14. Article
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Melissa Trotman-LucasSchool of Psychology, University of Nottingham, Nottingham, NG7 2UH, UK.ORCID 0000-0002-7735-7476
Claire L GibsonSchool of Psychology, University of Nottingham, Nottingham, NG7 2UH, UK.ORCID 0000-0002-3358-7341
University of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral ischemic stroke is a leading cause of death and disability, but current pharmacological therapies are limited in their utility and effectiveness.

Indexed as

Brain IschemiaStrokeAnimalsDisease Models, AnimalInfarction, Middle Cerebral ArteryReperfusionfocal ischemiain vivoischemiarefinementStroke

Identifiers

PMID34046164
PMCPMC8127011.2
OpenAlexW3140977970

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.