Evidence map›Paper›PMID 34046111›Full record

ArticleCardiology research2021

Association Between Constipation and Frailty Components in Patients Undergoing Late Phase II Cardiac Rehabilitation.

Miho Nishitani-Yokoyama, Kazunori Shimada, Miki Yamada, Akio Honzawa, Mitsuhiro Kunimoto, Yurina Sugita, Kei Fujiwara, Tomomi Matsubara, Rie Matsumori, Abidan Abulimiti and 9 more

Open access · diamondAbstract read
In one paragraph

Article in Cardiology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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  5. Frontiers in cellular and infection microbiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 2 institutions in 1 country.

Miho Nishitani-YokoyamaDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kazunori ShimadaDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Miki YamadaCardiovascular Rehabilitation and Fitness, Juntendo University Hospital, Tokyo, Japan.
Akio HonzawaCardiovascular Rehabilitation and Fitness, Juntendo University Hospital, Tokyo, Japan.
Mitsuhiro KunimotoDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Yurina SugitaDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Kei FujiwaraDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tomomi MatsubaraDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Rie MatsumoriDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Abidan AbulimitiDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Akie ShimadaDepartment of Cardiovascular Surgery, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Taira YamamotoDepartment of Cardiovascular Surgery, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tohru AsaiDepartment of Cardiovascular Surgery, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Atsushi AmanoDepartment of Cardiovascular Surgery, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Masakazu SaitohJuntendo University, Faculty of Health Science, Tokyo, Japan.
Tomoyuki MorisawaJuntendo University, Faculty of Health Science, Tokyo, Japan.
Tetsuya TakahashiJuntendo University, Faculty of Health Science, Tokyo, Japan.
Hiroyuki DaidaDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Tohru MinaminoDepartment of Cardiovascular Biology and Medicine, Juntendo University Graduate School of Medicine, Tokyo, Japan.
Juntendo University · JPJuntendo University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Japanese Ministry of Health, Labour and Welfare reported that the overall constipation complaint rates among men and women are 2.5% and 4.6%, respectively. To evaluate the impact of constipation on patients with cardiovascular diseases, we investigated the association between constipation and frailty components in patients undergoing cardiac rehabilitation (CR).

methodsWe enrolled 102 consecutive patients undergoing late phase II CR (mean age: 62.7 ± 13.4 years; 68 (67%) were men). We investigated clinical characteristics, observed defecation status and evaluated frailty components assessed by the Kihon checklist. According to the Clinical Guidelines for Chronic Constipation, the subjects were divided into constipation and non-constipation groups.

resultsConstipation was noted in 33 patients (32%). Interestingly, the constipation complaint rate was only 15%. Age was significantly higher in the constipation group than in the non-constipation group; however, no differences in sex, underlying diseases and prevalence rates of coronary risk factors were observed between the two groups. Body mass index, hemoglobin level, albumin level and estimated glomerular filtration rate were significantly lower in the constipation group than in the non-constipation group. The prevalence of frailty was significantly higher in the constipation group than in the non-constipation group. Physical ability, seclusion and depression scores were significantly higher in the constipation group than the non-constipation group.

conclusionsConstipation was associated with physical function and depression score as components of frailty in patients undergoing CR.

Indexed as

Cardiac rehabilitationCardiovascular diseaseConstipationDefecationFrailty

Identifiers

PMID34046111
PMCPMC8139749
OpenAlexW3161448010

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.