Evidence map›Paper›PMID 34046101›Full record

ArticleWorld journal of oncology2021

A Case of Refractory Esophageal Ulcer Caused by Radiotherapy for Hepatocellular Carcinoma.

Kazu Hamada, Tohru Itoh, Ken Kawaura, Hiroaki Kuno, Junji Kamai, Rika Kobayasi, Sadahumi Azukisawa, Hidekazu Kitakata, Taishi Ishisaka, Yuta Igarashi and 11 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Kazu HamadaDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Tohru ItohDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Ishikawa, Japan.
Ken KawauraDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Ishikawa, Japan.
Hiroaki KunoDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Ishikawa, Japan.
Junji KamaiDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Ishikawa, Japan.
Rika KobayasiDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Ishikawa, Japan.
Sadahumi AzukisawaDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Ishikawa, Japan.
Hidekazu KitakataDepartment of Gastroenterological Endoscopy, Kanazawa Medical University, Ishikawa, Japan.
Taishi IshisakaDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Yuta IgarashiDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Kumie KoderaDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Tazuo OkunoDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Takuro MoritaDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Tarou HimenoDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Hiroshi YanoDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Toshihiro HigashikawaDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Osamu IritaniDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Kunimitsu IwaiDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Shigeto MorimotoDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Munetaka MatobaDepartment of Radiology, Kanazawa Medical University, Ishikawa, Japan.
Masashi OkuroDepartment of Geriatric Medicine, Kanazawa Medical University, Ishikawa, Japan.
Kanazawa Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 77-year-old man who underwent radiotherapy for hepatocellular carcinoma 6 months prior consulted for esophageal obstruction. Esophagogastroduodenoscopy revealed an esophageal ulcer caused by radiotherapy for hepatocellular carcinoma. He was treated with dietary counseling and vonoprazan. After 9 months, the ulcer improved but a moderate stenosis remained. Several factors such as high fraction size, history of chemotherapy, and stress associated with food intake might involve in the development of a radiation-associated ulcer. Opportunities to choose radiotherapy for hepatocellular carcinoma may increase, so we hypothesize that esophageal ulcers might be a complication that should be noted associated with this therapy.

Indexed as

Chronic esophageal toxicityEsophageal stenosisEsophageal ulcerHepatocellular carcinomaRadiotherapy

Identifiers

PMID34046101
PMCPMC8139740
OpenAlexW3163558910

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.