ArticleNature biomedical engineering2021
Miniaturized electromechanical devices for the characterization of the biomechanics of deep tissue.
Article in Nature biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 127 citations in OpenAlex.
- A wearable biomechanical system for medical evaluation of soft tissue disorders.Science advances · 2026Article
- Synthetic materials trained tactile sensing enables quantitative perception of Young's modulus and Poisson's ratio.Nature communications · 2026Article
- Design and Implementation of an Electromagnetic-Capacitive Coupling Mechanism-Based Material Young's Modulus Measurement System.Materials (Basel, Switzerland) · 2026Article
- Mechanomedicine.Nature reviews bioengineering · 2026Article
- The Electromechanical Connectome: Integrating Voltage, Mechanical Nano-Forces, and Subcellular Fluid Phase Dynamics in Human Neural Computation.International journal of molecular sciences · 2026Review
- A Wearable System Featuring Biomimetic Spatially Distributed Iontronic Sensing Array for Dynamic Monitoring of Deep Tissue Modulus.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Skin-Integrated Soft Wearable XR Interfaces for Seamless and Realistic User Experience.Chemical reviews · 2025Review
- Wireless, wearable elastography via mechano-acoustic wave sensing for ambulatory monitoring of tissue stiffness.Science advances · 2025Article
- A skin-interfaced three-dimensional closed-loop sensing and therapeutic electronic wound bandage.Nature communications · 2025Article
- Transforming Healthcare: Intelligent Wearable Sensors Empowered by Smart Materials and Artificial Intelligence.Advanced materials (Deerfield Beach, Fla.) · 2025Review
- Flexible bioelectronic systems with large-scale temperature sensor arrays for monitoring and treatments of localized wound inflammation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Near-infrared spectroscopy-enabled electromechanical systems for fast mapping of biomechanics and subcutaneous diagnosis.Science advances · 2024Article
- Mormyroidea-inspired electronic skin for active non-contact three-dimensional tracking and sensing.Nature communications · 2024Article
- Article
- Wearable bio-adhesive metal detector array (BioMDA) for spinal implants.Nature communications · 2024Article
- A seamless living biointerface for inflammation management.National science review · 2024Article
- Editorial for the Special Issue on Wearable and Implantable Bio-MEMS Devices and Applications.Micromachines · 2024Article
- Quantitative softness and texture bimodal haptic sensors for robotic clinical feature identification and intelligent picking.Science advances · 2024Article
- Motion artefact management for soft bioelectronics.Nature reviews bioengineering · 2024Article
- Article
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Authors and funding
27 authors at 8 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Evaluating the biomechanics of soft tissues at depths well below their surface, and at high precision and in real time, would open up diagnostic opportunities. Here, we report the development and application of miniaturized electromagnetic devices, each integrating a vibratory actuator and a soft strain-sensing sheet, for dynamically measuring the Young's modulus of skin and of other soft tissues at depths of approximately 1-8 mm, depending on the particular design of the sensor. We experimentally and computationally established the operational principles of the devices and evaluated their performance with a range of synthetic and biological materials and with human skin in healthy volunteers. Arrays of devices can be used to spatially map elastic moduli and to profile the modulus depth-wise. As an example of practical medical utility, we show that the devices can be used to accurately locate lesions associated with psoriasis. Compact electronic devices for the rapid and precise mechanical characterization of living tissues could be used to monitor and diagnose a range of health disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.