Evidence map›Paper›PMID 34045101›Full record

ArticleVaccine2021

A systems map of the economic considerations for vaccination: Application to hard-to-reach populations.

Sarah N Cox, Patrick T Wedlock, Sarah W Pallas, Elizabeth A Mitgang, Tatenda T Yemeke, Sarah M Bartsch, Taiwo Abimbola, Sheryl S Sigemund, Aaron Wallace, Sachiko Ozawa and 1 more

Open access · greenAbstract read
In one paragraph

Article in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. A Systems Map of the Challenges of Climate Communication.Journal of health communication · 2024
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Sarah N CoxPublic Health Informatics, Computational, and Operations Research (PHICOR), City University of New York (CUNY) Graduate School of Public Health and Health Policy, New York City, NY, United States.
Patrick T WedlockPublic Health Informatics, Computational, and Operations Research (PHICOR), City University of New York (CUNY) Graduate School of Public Health and Health Policy, New York City, NY, United States.
Sarah W PallasGlobal Immunization Division, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States.
Elizabeth A MitgangPublic Health Informatics, Computational, and Operations Research (PHICOR), City University of New York (CUNY) Graduate School of Public Health and Health Policy, New York City, NY, United States.
Tatenda T YemekeDivision of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, United States.
Sarah M BartschPublic Health Informatics, Computational, and Operations Research (PHICOR), City University of New York (CUNY) Graduate School of Public Health and Health Policy, New York City, NY, United States.
Taiwo AbimbolaGlobal Immunization Division, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States.
Sheryl S SigemundPublic Health Informatics, Computational, and Operations Research (PHICOR), City University of New York (CUNY) Graduate School of Public Health and Health Policy, New York City, NY, United States.
Aaron WallaceGlobal Immunization Division, Centers for Disease Control and Prevention (CDC), Atlanta, GA, United States.
Sachiko OzawaDivision of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, United States; Department of Maternal and Child Health, UNC Gillings School of Global Health, University of North Carolina, Chapel Hill, NC, United States.
Bruce Y LeePublic Health Informatics, Computational, and Operations Research (PHICOR), City University of New York (CUNY) Graduate School of Public Health and Health Policy, New York City, NY, United States. Electronic address: bruceleemdmba@gmail.com.
City University of New York · USCenters for Disease Control and Prevention · USUniversity of North Carolina at Chapel Hill · USThe Graduate Center, CUNY · US

Funding

Virtual Population Obesity Prevention (VPOP) Labs: Computational, Multi-Scale Models for Obesity SolutionsU01HD086861 · NICHD · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2015 to 2019
$2.8M
Regional Healthcare Ecosystem Analyst for Healthcare Associated InfectionsR01HS023317 · AHRQ · JOHNS HOPKINS UNIVERSITY · PI LEE, BRUCE Y · 2014 to 2014
$2.4M
Regional Healthcare Ecosystem Analyst (RHEA) Modeling the Environment (MODE): SARS-CoV-2R01GM127512 · NIGMS · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI LEE, BRUCE Y · 2020 to 2023
$2.1M
MOdeling Nursing homes to Affect Response to COVID-19 (MONARC)R01HS028165 · AHRQ · GRADUATE SCHOOL OF PUBLIC HEALTH AND HEALTH POLICY · PI LEE, BRUCE Y · 2021 to 2022
$993k
AHRQ HHS R01 HS023317AHRQ HHS R01 HS028165NICHD NIH HHS U01 HD086861NIGMS NIH HHS R01 GM127512
6 · The paper itself

Abstract

backgroundUnderstanding the economics of vaccination is essential to developing immunization strategies that can be employed successfully with limited resources, especially when vaccinating populations that are hard-to-reach.

methodsBased on the input from interviews with 24 global experts on immunization economics, we developed a systems map of the mechanisms (i.e., necessary steps or components) involved in vaccination, and associated costs and benefits, focused at the service delivery level. We used this to identify the mechanisms that may be different for hard-to-reach populations.

resultsThe systems map shows different mechanisms that determine whether a person may or may not get vaccinated and the potential health and economic impacts of doing so. The map is divided into two parts: 1) the costs of vaccination, representing each of the mechanisms involved in getting vaccinated (n = 23 vaccination mechanisms), their associated direct vaccination costs (n = 18 vaccination costs), and opportunity costs (n = 5 opportunity costs), 2) the impact of vaccination, representing mechanisms after vaccine delivery (n = 13 impact mechanisms), their associated health effects (n = 10 health effects for beneficiary and others), and economic benefits (n = 13 immediate and secondary economic benefits and costs). Mechanisms that, when interrupted or delayed, can result in populations becoming hard-to-reach include getting vaccines and key stakeholders (e.g., beneficiaries/caregivers, vaccinators) to a vaccination site, as well as vaccine administration at the site.

conclusionDecision-makers can use this systems map to understand where steps in the vaccination process may be interrupted or weak and identify where gaps exist in the understanding of the economics of vaccination. With improved understanding of system-wide effects, this map can help decision-makers inform targeted interventions and policies to increase vaccination coverage in hard-to-reach populations.

Indexed as

VaccinationVaccinesHumansImmunizationImmunization ProgramsVaccination CoverageVaccinesEconomic benefitsHard-to-reachSystems mapVaccination costs

Identifiers

PMID34045101
PMCPMC8889938
OpenAlexW3164575910

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.