Evidence map›Paper›PMID 34044871›Full record

ArticleJournal of orthopaedic surgery and research2021

Gastrocnemius muscle flap with vancomycin/gentamicin-calcium sulfate and autogenous iliac bone graft for the phase I treatment of localized osteomyelitis after tibial plateau fracture surgery.

Weiwei Ruan, Menglu Li, Qiaofeng Guo, Bingyuan Lin

Open access · goldAbstract read
In one paragraph

Article in Journal of orthopaedic surgery and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Weiwei RuanDepartment of Orthopedics, Tongde Hospital of Zhejiang Provincial, Zhejiang Academy of Traditional Chinese Medicine, No. 234 Gucui Road, Hangzhou, 310002, Zhejiang, People's Republic of China.ORCID https://orcid.org/0000-0001-7725-5763
Menglu LiInstitute of Cancer Research and Basic Medical Sciences, Cancer Hospital of University Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, People's Republic of China.
Qiaofeng GuoDepartment of Orthopedics, Tongde Hospital of Zhejiang Provincial, Zhejiang Academy of Traditional Chinese Medicine, No. 234 Gucui Road, Hangzhou, 310002, Zhejiang, People's Republic of China.
Bingyuan LinDepartment of Orthopedics, Tongde Hospital of Zhejiang Provincial, Zhejiang Academy of Traditional Chinese Medicine, No. 234 Gucui Road, Hangzhou, 310002, Zhejiang, People's Republic of China. hztdboneage@163.com.ORCID http://orcid.org/0000-0001-9267-2661
Tongde Hospital of Zhejiang Province · CNZhejiang Cancer Hospital · CNZhejiang Provincial Hospital of TCM · CN

Funding

Natural Science Foundation of Zhejiang Province LY20H270002Zhejiang Traditional Chinese Medicine Administration 2021ZB060
6 · The paper itself

Abstract

purposeTo investigate the clinical effect of gastrocnemius muscle flaps combined with vancomycin/gentamicin-calcium sulfate combined and autologous iliac bone graft in the phase I treatment of traumatic focal osteomyelitis (Cierny-Mader type III) after tibial plateau fracture surgery.

methodsFrom July 2009 to January 2018, 35 patients with localized osteomyelitis (Cierny-Mader type III) who met the inclusion criteria were followed up and treated. All patients were infected after undergoing internal fracture fixation surgery. Among them, 18 cases were plate-exposed, 14 cases were due to sinus tracts, two were due to skin necrosis, and one was bone-exposed. We treated patients with several measures. All cases were then followed up. The follow-up indicators included Hospital for Special Surgery knee scores (HSS), the time of laying drainage pipe, bone healing time, infection control rate, and the incidence of nonunion and other complications.

resultsAll patients were followed up for 24-60 months. None of them underwent amputation. For repairing soft tissue defects, 17 cases were covered with a muscle flap using the medial head of gastrocnemius alone, 15 cases were treated with the lateral head of gastrocnemius muscle, and three cases were covered with the combination of the two heads. Compared to the preoperative score, we found that the average HSS improved at the 1-year and 2-year follow-up (54 vs. 86 vs. 87).

conclusionUsing a gastrocnemius muscle flap combined with vancomycin/gentamicin-calcium sulfate and autogenous iliac bone was an effective method for the phase I treatment of osteomyelitis (Cierny-Mader type III) after tibial plateau fracture surgery. In the primary treatment of focal traumatic osteomyelitis, it can decrease the treatment time, number of surgeries, pain of patients, time of bone healing, postoperative exudation, and infection recurrence rate and increase the healing bone's strength.

Indexed as

AdultAgedAged, 80 and overAnti-Bacterial AgentsBone TransplantationCalcium SulfateCombined Modality TherapyFemaleFracture Fixation, InternalGentamicinsHumansIliumMaleMiddle AgedMuscle, SkeletalOsteomyelitisAnti-Bacterial AgentsCalcium SulfateGentamicinsVancomycinBone graftGastrocnemius muscle flapsOsteomyelitisPhase ITibial plateau fracturesVancomycin

Identifiers

PMID34044871
PMCPMC8157409
OpenAlexW3126324655

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.