ArticleBMC public health2021
Relationships between age at first substance use and persistence of cannabis use and cannabis use disorder.
Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- The role of perceived access to cannabis in the association between friends who use cannabis and adolescent initiation: A longitudinal analysis from the Canadian COMPASS study.Addiction (Abingdon, England) · 2026Observational
- Who is at risk? Core mental health symptoms and problematic cannabis use in Germany.Journal of cannabis research · 2026Article
- Age-Related Effects of Cannabis and Cannabinoids on Brain and Behavior.Cannabis and cannabinoid research · 2026Review
- Pharmacotherapy for Cannabis Use Disorder: Preclinical and Clinical Models.Current topics in behavioral neurosciences · 2026Review
- Childhood events as factors in continued cannabis use in adulthood: a longitudinal study of a 30-year follow-up cohort.Journal of cannabis research · 2025Article
- Cannabis involvement in posttraumatic stress disorder emergency department visits after cannabis legalization.The American journal on addictions · 2025Article
- The Relationships of Early Use of Marijuana With Substance Use and Violence in Adolescent Gamblers and Non-Gamblers.Journal of the Korean Academy of Child and Adolescent Psychiatry · 2025Article
- Polygenic Risk for Substance Use Disorders as Predictors of Substance Use Initiation Among African American Youth.Journal of studies on alcohol and drugs · 2025Article
- Three-day delta-9-tetrahydrocannabinol (THC) exposure eliminates long-term depression in ventral tegmental area of young, but not adult mice.Journal of cannabis research · 2025Article
- Association of childhood mental health and cognition with longitudinal patterns of cannabis problems in adolescence.Psychological medicine · 2025Article
- Racism and cannabis-related problems among Black adults who smoke cigarettes: The role of negative emotions in responses to experiencing racism.Experimental and clinical psychopharmacology · 2025Article
- Post-legalization shifts in cannabis use among young adults in Georgia-A nationally representative study.Addiction (Abingdon, England) · 2025Article
- Missouri College Students' Intentions Towards Initiating or Changing Cannabis Use in a Shifting Legal Landscape.Cannabis (Albuquerque, N.M.) · 2025Article
- Age of tobacco, nicotine and cannabis use initiation in Switzerland: a sequence analysis among adolescents and young adults.BMC public health · 2024Article
- Review
- Academic orientation and cannabis use-findings from a population-based study of Swedish adolescents in upper secondary school.European journal of public health · 2024Article
- Trends in Norwegian adolescents' substance use between 2014 and 2022: socioeconomic and gender differences.BMC public health · 2024Article
- Genetic influences and causal pathways shared between cannabis use disorder and other substance use traits.Molecular psychiatry · 2024Article
- Lifetime use of alcohol and cannabis among U.S. adolescents across age: Exploring differential patterns by sex and race/ethnicity using the 2019 NSDUH data.Drug and alcohol dependence reports · 2024Article
- Explanatory factors of polydrug use in mid-late teens and the relevance of information sources: Correlational and configurational assessment in Tarragona (Spain).AIMS public health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrom a secondary prevention perspective, it is useful to know who is at greatest risk of progressing from substance initiation to riskier patterns of future use. Therefore, the aim of this study was to determine relationships between age at first use of alcohol, tobacco and cannabis and patterns of cannabis use, frequency of use and whether age of substance use onset is related to having a cannabis use disorder (CUD).
methodsWe analysed data from Ireland's 2010/11 and 2014/15 National Drug Prevalence Surveys, which recruited 5134 and 7005 individuals respectively, aged 15 years and over, living in private households. We included only those people who reported lifetime cannabis use. Multinomial, linear and binary logistic regression analyses were used to determine relationships between age of substance use onset and patterns of cannabis use, frequency of use and having a CUD.
resultsWhen compared to former users, the odds of being a current cannabis user were found to be reduced by 11% (OR = 0.89; 95% CI: 0.83, 0.95) and 4% (OR = 0.96; 95% CI: 0.92, 1.00) for each year of delayed alcohol and cannabis use onset, respectively. Among current users, significant inverse linear relationships were noted, with increasing age of first use of tobacco (β = - 0.547; P < .001) and cannabis (β = - 0.634; P < .001) being associated with a decreased frequency of cannabis use within the last 30 days. The odds of having a CUD were found to be reduced by 14% (OR = 0.86; 95% CI: 0.78, 0.94) and 11% (OR = 0.89; 95% CI: 0.82, 0.98) for each year of delayed tobacco and cannabis use onset respectively in analyses which examined survey participants aged 15-34 years.
conclusionsAmong people who report past cannabis use, it is those with a more precocious pattern of early use of substances, including alcohol, and especially tobacco and cannabis, who are more likely to report ongoing, heavy and problematic cannabis use. Secondary prevention initiatives should prioritise people with a pattern of very early onset substance use.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.