Evidence map›Paper›PMID 34044582›Full record

ArticleBone & joint open2021

Follow-up definitions in clinical orthopaedic research : a systematic review.

Sufian S Ahmad, Lorenz Hoos, Carsten Perka, Ulrich Stöckle, Karl F Braun, Christian Konrads

Abstract read
In one paragraph

Article in Bone & joint open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Outcome of avulsion fractures in the foot after supination trauma: A systematic review.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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  11. Proximal femoral replacement for oncologic and non-oncologic indications: a retrospective study over a 13-year period.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sufian S AhmadCenter for Musculoskeletal Surgery, Charité - University Medical Center Berlin, Berlin, Germany.ORCID https://orcid.org/0000-0001-9763-092X
Lorenz HoosDepartment of Trauma and Reconstructive Surgery, BG Klinik, Eberhard Karls University Tübingen, Tubingen, Germany.
Carsten PerkaCenter for Musculoskeletal Surgery, Charité - University Medical Center Berlin, Berlin, Germany.
Ulrich StöckleCenter for Musculoskeletal Surgery, Charité - University Medical Center Berlin, Berlin, Germany.
Karl F BraunCenter for Musculoskeletal Surgery, Charité - University Medical Center Berlin, Berlin, Germany.
Christian KonradsDepartment of Trauma and Reconstructive Surgery, BG Klinik, Eberhard Karls University Tübingen, Tubingen, Germany.ORCID https://orcid.org/0000-0002-1285-4615

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsThe follow-up interval of a study represents an important aspect that is frequently mentioned in the title of the manuscript. Authors arbitrarily define whether the follow-up of their study is short-, mid-, or long-term. There is no clear consensus in that regard and definitions show a large range of variation. It was therefore the aim of this study to systematically identify clinical research published in high-impact orthopaedic journals in the last five years and extract follow-up information to deduce corresponding evidence-based definitions of short-, mid-, and long-term follow-up.

methodsA systematic literature search was performed to identify papers published in the six highest ranked orthopaedic journals during the years 2015 to 2019. Follow-up intervals were analyzed. Each article was assigned to a corresponding subspecialty field: sports traumatology, knee arthroplasty and reconstruction, hip-preserving surgery, hip arthroplasty, shoulder and elbow arthroplasty, hand and wrist, foot and ankle, paediatric orthopaedics, orthopaedic trauma, spine, and tumour. Mean follow-up data were tabulated for the corresponding subspecialty fields. Comparison between means was conducted using analysis of variance.

resultsOf 16,161 published articles, 590 met the inclusion criteria. Of these, 321 were of level IV evidence, 176 level III, 53 level II, and 40 level I. Considering all included articles, a long-term study published in the included high impact journals had a mean follow-up of 151.6 months, a mid-term study of 63.5 months, and a short-term study of 30.0 months.

conclusionThe results of this study provide evidence-based definitions for orthopaedic follow-up intervals that should provide a citable standard for the planning of clinical studies. A minimum mean follow-up of a short-term study should be 30 months (2.5 years), while a mid-term study should aim for a mean follow-up of 60 months (five years), and a long-term study should aim for a mean of 150 months (12.5 years). Level of Evidence: Level I. Cite this article:

Indexed as

Clinical studyLong-termMid-termOutcomeShort-termStudy design

Identifiers

PMID34044582
PMCPMC8168549

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.