Evidence map›Paper›PMID 34044530›Full record

ArticleZhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns2021

[Research advances on the role and mechanism of inflammatory response in the formation of hypertrophic scars and keloids].

H T Wang, J T Han, D H Hu

Open access · greenAbstract read
In one paragraph

Article in Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. [Zhonghua shao shang yu chuang mian xiu fu za zhi · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

H T WangDepartment of Burns and Cutaneous Surgery, Burn Center of PLA, the First Affiliated Hospital of Air Force Medical University, Xi'an 710032, China.
J T HanDepartment of Burns and Cutaneous Surgery, Burn Center of PLA, the First Affiliated Hospital of Air Force Medical University, Xi'an 710032, China.
D H HuDepartment of Burns and Cutaneous Surgery, Burn Center of PLA, the First Affiliated Hospital of Air Force Medical University, Xi'an 710032, China.
Burn Institute · US

Funding

General Program of National Natural Science Foundation of China 81971835General Program of Natural Science Foundation of Shaanxi Province of China 2014JM4180
6 · The paper itself

Abstract

Hypertrophic scars and keloids are common sequelae after wound healing, with a high incidence, which seriously affect the patient's quality of life. However, there is still a lack of effective prevention and treatment methods, mainly because the pathogenesis of scars is not clear. Current research believe that inflammatory response plays a critical role in the process of scar formation, and through the researches on the mechanisms it is hopeful to find new potential therapeutic drug targets for the prevention and treatment of hypertrophic scars and keloids. This article mainly reviews the research progresses on the role and mechanism of inflammatory cytokines and inflammatory cells in the formation of hypertrophic scars and keloids, as well as drugs, microRNAs, and exosomes, etc., for the treatment of hypertrophic scars and keloids by inhibiting inflammatory response.

Indexed as

Cicatrix, HypertrophicKeloidCytokinesHumansQuality of LifeWound HealingCytokines

Identifiers

PMID34044530
PMCPMC11917354
OpenAlexW3165788552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.