Evidence map›Paper›PMID 34044499›Full record

ArticleJournal of clinical research in pediatric endocrinology2022

Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked Syndrome in Two Siblings: Same Mutation But Different Clinical Manifestations at Onset

Gülay Karagüzel, Recep Polat, Mehtap H Abul, Alper Han Cebi, Fazıl Orhan

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical research in pediatric endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gülay KaragüzelKaradeniz Technical University Faculty of Medicine, Department of Pediatric Endocrinology, Trabzon, TurkeyORCID 0000-0003-4116-5365
Recep PolatKaradeniz Technical University Faculty of Medicine, Department of Pediatric Endocrinology, Trabzon, TurkeyORCID 0000-0002-3786-0739
Mehtap H AbulKaradeniz Technical University Faculty of Medicine, Department Pediatric Allergy and Immunology, Trabzon, TurkeyORCID 0000-0003-4298-6851
Alper Han CebiKaradeniz Technical University Faculty of Medicine, Department of Genetics, Trabzon, TurkeyORCID 0000-0001-7388-874X
Fazıl OrhanKaradeniz Technical University Faculty of Medicine, Department Pediatric Allergy and Immunology, Trabzon, TurkeyORCID 0000-0002-4850-932X
Karadeniz Technical University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is an early onset systemic autoimmune genetic disorder caused by mutation of the

Indexed as

Diabetes Mellitus, Type 1Genetic Diseases, X-LinkedIntestinal DiseasesPolyendocrinopathies, AutoimmuneDiarrheaForkhead Transcription FactorsHumansImmune System DiseasesMutationSiblingsSyndromeForkhead Transcription FactorsImmune dysregulation polyendocrinopathy enteropathy X-linked syndromeneonatal diabetesrenal disease

Identifiers

PMID34044499
PMCPMC9422912
OpenAlexW3164488294

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.