ArticleInternational neurourology journal2021
What is the Cause of Recurrent Urinary Tract Infection? Contemporary Microscopic Concepts of Pathophysiology.
Article in International neurourology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- UropathogenicAntibiotics (Basel, Switzerland) · 2026Review
- Vaginal microbiota and urinary tract infections in women: the protective role of vaginal lactobacilli in counteracting urinary tract infections occurrence and recurrence.Le infezioni in medicina · 2026Review
- More than an infection: the ecological puzzle of recurrent urinary tract infections.Frontiers in cellular and infection microbiology · 2026Review
- A New Bromelain-Based Polyenzymatic Complex Plus N-Acetylcysteine: A Promising Approach for the Treatment of Urinary Tract Infections.International journal of molecular sciences · 2025Article
- Investigation of the predictive value of Hounsfield units in predicting stone culture results in urinary stone disease.Scientific reports · 2025Article
- Influence of bacterial morphotype on urine culture and molecular epidemiological differences inMicrobiology spectrum · 2025Article
- Recurrent Urinary Tract Infections (UTIs): A Review and Proposal for Clinicians.Antibiotics (Basel, Switzerland) · 2025Article
- The Critical Role of Intracellular Bacterial Communities in Uncomplicated Recurrent Urinary Cystitis: A Comprehensive Review of Detection Methods and Diagnostic Potential.International neurourology journal · 2024Article
- Urinary tract infection: is it time for a new approach considering a gender perspective and new microbial advances?Frontiers in urology · 2024Review
- Incidence and Recurrence of Urinary Tract Infections Caused by UropathogenicResearch and reports in urology · 2024Article
- Improved Detection of Urolithiasis Using High-Resolution Computed Tomography Images by a Vision Transformer Model.International neurourology journal · 2023Article
- Microbiota Ecosystem in Recurrent Cystitis and the Immunological Microenvironment of Urothelium.Healthcare (Basel, Switzerland) · 2023Review
- Antimicrobial Activity of Spices Popularly Used in Mexico against Urinary Tract Infections.Antibiotics (Basel, Switzerland) · 2023Review
- Comparative genomic analysis of uropathogenicFrontiers in microbiology · 2023Article
- The Urobiome and Its Role in Overactive Bladder.International neurourology journal · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
Urinary tract infections (UTIs) are the most common infectious disease and are mainly caused by Escherichia coli. In this review, we introduce the current concept of recurrent UTI (rUTI) based on recent research dealing with pathophysiology of the disease. Although urine is considered sterile, recent studies dealing with microbiome have proposed different ideas. UTIs have typically been considered as extracellular infections, but recently, uropathogenic Escherichia coli (UPEC) has been shown to bind and replicate in the urothelium to make intracellular bacterial communities. Binding UPECs might proceed in many ways including extracellular expulsion for clearance or survival and quiescent intracellular reservoirs that can cause rUTI. Moreover, it is also suggested that other important factors, such as lipopolysaccharide and multimicrobial infection, can be the cause of rUTI. This review article reveals a key mechanism of recurrence and discusses what makes a pathway of resolution or recurrence in a host after initial infection.
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Registered trials
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