Evidence map›Paper›PMID 34043338›Full record

ArticleBioconjugate chemistry2021

Structure-Activity Relationship of Fluorinated Sialic Acid Inhibitors for Bacterial Sialylation.

Sam J Moons, Emiel Rossing, Jurriaan J A Heming, Mathilde A C H Janssen, Monique van Scherpenzeel, Dirk J Lefeber, Marien I de Jonge, Jeroen D Langereis, Thomas J Boltje

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioconjugate chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Synthesis and Antiproliferative Activity of FluorinatedThe Journal of organic chemistry · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sam J MoonsCluster of Molecular Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen 6525 AJ, The Netherlands.
Emiel RossingCluster of Molecular Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen 6525 AJ, The Netherlands.
Jurriaan J A HemingCluster of Molecular Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen 6525 AJ, The Netherlands.
Mathilde A C H JanssenCluster of Molecular Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen 6525 AJ, The Netherlands.
Monique van ScherpenzeelTranslational Metabolic Laboratory, Department of Neurology, Donders Center for Brain Cognition and Behavior, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.
Dirk J LefeberTranslational Metabolic Laboratory, Department of Neurology, Donders Center for Brain Cognition and Behavior, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.
Marien I de JongeLaboratory of Medical Immunology, Radboud Center for Infectious Diseases, Radboud Institute for Molecular Sciences, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.
Jeroen D LangereisLaboratory of Medical Immunology, Radboud Center for Infectious Diseases, Radboud Institute for Molecular Sciences, Radboud University Medical Center, Nijmegen 6525 GA, The Netherlands.
Thomas J BoltjeCluster of Molecular Chemistry, Institute for Molecules and Materials, Radboud University Nijmegen, Nijmegen 6525 AJ, The Netherlands.ORCID 0000-0001-9141-8784

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial pathogens such as Nontypeable

Indexed as

HalogenationHaemophilus influenzaeN-Acetylneuraminic AcidStructure-Activity RelationshipN-Acetylneuraminic Acid

Identifiers

PMID34043338
PMCPMC8382218

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.