Evidence map›Paper›PMID 34043152›Full record

ArticleJournal of thrombosis and thrombolysis2022

Sickle cell disease related chronic thromboembolic pulmonary hypertension: challenging clinical scenario.

Panagiotis Karyofyllis, Dimitrios Tsiapras, Eftychia Demerouti, Iakovos Armenis, Varvara Papadopoulou, Vassilis Voudris

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Journal of thrombosis and thrombolysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Panagiotis KaryofyllisDepartment of Interventional Cardiology, Onassis Cardiac Surgery Center, Syggrou 356 Avenue, Kallithea, 17674, Athens, Attiki, Greece. pakar768@yahoo.gr.ORCID http://orcid.org/0000-0002-0717-8544
Dimitrios TsiaprasDepartment of Non-Invasive Diagnostics, Onassis Cardiac Surgery Center, Athens, Attiki, Greece.
Eftychia DemeroutiDepartment of Non-Invasive Diagnostics, Onassis Cardiac Surgery Center, Athens, Attiki, Greece.
Iakovos ArmenisDepartment of Non-Invasive Diagnostics, Onassis Cardiac Surgery Center, Athens, Attiki, Greece.
Varvara PapadopoulouDepartment of Non-Invasive Diagnostics, Onassis Cardiac Surgery Center, Athens, Attiki, Greece.
Vassilis VoudrisDepartment of Interventional Cardiology, Onassis Cardiac Surgery Center, Syggrou 356 Avenue, Kallithea, 17674, Athens, Attiki, Greece.
Onassis Cardiac Surgery Center · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sickle cell disease (SCD), a haemoglobinopathy characterized by chronic haemolysis with acute exacerbations and vascular occlusion episodes, may be complicated by pulmonary hypertension. The latter may be caused by chronic thromboembolic disease of pulmonary artery branches and its management is not well-defined. Herein, we present a case of SCD complicated by chronic thromboembolic pulmonary hypertension of subsegmental pulmonary artery branches successfully treated with endothelin receptor antagonists, orally administered prostacyclin analogs and balloon pulmonary angioplasty. This challenging case highlights the need for clinical awareness of chronic thromboembolic pulmonary hypertension as a specific and potentially curable form of pulmonary hypertension complicating SCD course that may necessitate combined pharmacologic and interventional management.

Indexed as

Anemia, Sickle CellAngioplasty, BalloonHypertension, PulmonaryPulmonary EmbolismChronic DiseaseHumansPulmonary ArteryBalloon pulmonary angioplastyChronic thromboembolic pulmonary hypertensionEndothelin receptor antagonistOral prostacyclin agonistSickle cell disease

Identifiers

PMID34043152
OpenAlexW3164200312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.