Evidence map›Paper›PMID 34042773›Full record

ArticleStudies in health technology and informatics2021

Evaluating Site-Level Implementations of the HL7 FHIR Standard to Support eSource Data Exchange in Clinical Research.

Maryam Y Garza, Michael W Rutherford, Bhargav Adagarla, Eric Eisenstein, Karan R Kumar, Kanecia O Zimmerman, Umit Topaloglu, Meredith Zozus

Abstract read
In one paragraph

Article in Studies in health technology and informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. HL7 FHIR-based tools and initiatives to support clinical research: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2022
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maryam Y GarzaUniversity of Arkansas for Medical Sciences, Little Rock, Arkansas.
Michael W RutherfordUniversity of Arkansas for Medical Sciences, Little Rock, Arkansas.
Bhargav AdagarlaDuke Clinical Research Institute, Duke University, Durham, North Carolina.
Eric EisensteinDuke Clinical Research Institute, Duke University, Durham, North Carolina.
Karan R KumarDuke Clinical Research Institute, Duke University, Durham, North Carolina.
Kanecia O ZimmermanDuke Clinical Research Institute, Duke University, Durham, North Carolina.
Umit TopalogluWake Forest University School of Medicine, Winston-Salem, North Carolina.
Meredith ZozusUniversity of Texas Health Science Center at San Antonio, San Antonio, Texas.

Funding

Wake Forest Clinical and Translational Science AwardUL1TR001420 · NCATS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI ARD, JAMY D, FOLEY, KRISTIE L · 2015 to 2023
$32.3M
Expanding Translational Research in ArkansasUL1TR003107 · NCATS · UNIV OF ARKANSAS FOR MED SCIS · PI JAMES, LAURA P · 2019 to 2023
$21.6M
NCATS NIH HHS UL1 TR001420NCATS NIH HHS UL1 TR003107NICHD NIH HHS HHSN275201000003INICHD NIH HHS HHSN275201800003I
6 · The paper itself

Abstract

Direct extraction and use of electronic health record (EHR) data is a long-term and multifaceted endeavor that includes design, development, implementation and evaluation of methods and tools for semi-automating tasks in the research data collection process, including, but not limited to, medical record abstraction (MRA). A systematic mapping of study data elements was used to measure the coverage of the Health Level Seven (HL7®) Fast Healthcare Interoperability Resources (FHIR®) standard for a federally sponsored, pragmatic cardiovascular randomized controlled trial (RCT) targeting adults. We evaluated site-level implementations of the HL7® FHIR® standard to investigate study- and site-level differences that could affect coverage and offer insight into the feasibility of a FHIR-based eSource solution for multicenter clinical research.

Indexed as

Electronic Health RecordsHealth Level Sevenclinical researchelectronic health recordseSourcehealth information exchangeHL7 FHIRinteroperability

Identifiers

PMID34042773
PMCPMC9137245

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.