Evidence map›Paper›PMID 34042604›Full record

ArticleJournal of medical Internet research2021

Patient Recruitment Into a Multicenter Clinical Cohort Linking Electronic Health Records From 5 Health Systems: Cross-sectional Analysis.

Wendy L Bennett, Carolyn T Bramante, Scott D Rothenberger, Jennifer L Kraschnewski, Sharon J Herring, Michelle R Lent, Jeanne M Clark, Molly B Conroy, Harold Lehmann, Nickie Cappella and 3 more

Registry-linked trialOpen access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02456090 (PaTH Clinical Data Research Network), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02456090 active not recruitingnot on this map

PaTH Clinical Data Research Network (CDRN) Study of Healthy Lifestyles and Health Care

Typeobservational_patient_registrySponsorUniversity of PittsburghRan2015 to 2030Enrolled1,500ConditionsWeight
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

  1. Trial
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  8. Transforming research recruitment: Leveraging EHR systems and patient portals.Journal of clinical and translational science · 2025
    Article
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  11. Implementation ofJournal of clinical and translational science · 2024
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Wendy L BennettJohns Hopkins University School of Medicine, Baltimore, MD, United States.ORCID 0000-0001-9828-0706
Carolyn T BramanteUniversity of Minnesota School of Medicine, Minneapolis, MN, United States.ORCID 0000-0001-5858-2080
Scott D RothenbergerUniversity of Pittsburgh, Pittsburgh, PA, United States.ORCID 0000-0001-8300-5947
Jennifer L KraschnewskiPenn State College of Medicine, Hershey, PA, United States.ORCID 0000-0003-0998-1346
Sharon J HerringLewis Katz School of Medicine, Philadelphia, PA, United States.ORCID 0000-0002-6136-521X
Michelle R LentGeisinger Health, Danville, PA, United States.ORCID 0000-0001-7892-1879
Jeanne M ClarkJohns Hopkins University School of Medicine, Baltimore, MD, United States.ORCID 0000-0003-1194-0092
Molly B ConroyUniversity of Utah School of Medicine, Salt Lake City, UT, United States.ORCID 0000-0003-0404-1371
Harold LehmannJohns Hopkins University School of Medicine, Baltimore, MD, United States.ORCID 0000-0002-7698-219X
Nickie CappellaUniversity of Pittsburgh, Pittsburgh, PA, United States.ORCID 0000-0003-3790-9464
Megan Gauvey-KernJohns Hopkins University School of Medicine, Baltimore, MD, United States.ORCID 0000-0003-1662-5243
Jody McCulloughPenn State College of Medicine, Hershey, PA, United States.ORCID 0000-0002-1675-534X
Kathleen M McTigueUniversity of Pittsburgh, Pittsburgh, PA, United States.ORCID 0000-0002-0752-1576
Johns Hopkins University · USUniversity of Pittsburgh · USPenn State Milton S. Hershey Medical Center · USGeisinger Health System · USUniversity of Minnesota · USUniversity of Utah · US

Funding

Research BaseP30DK072488 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI MITCHELL, BRAXTON D, TAYLOR, SIMEON I. · 2005 to 2019
$17.3M
NIDDK NIH HHS P30 DK072488
6 · The paper itself

Abstract

backgroundThere is growing interest in identifying and recruiting research participants from health systems using electronic health records (EHRs). However, few studies have described the practical aspects of the recruitment process or compared electronic recruitment methods to in-person recruitment, particularly across health systems.

objectiveThe objective of this study was to describe the steps and efficiency of the recruitment process and participant characteristics by recruitment strategy.

methodsEHR-based eligibility criteria included being an adult patient engaged in outpatient primary or bariatric surgery care at one of 5 health systems in the PaTH Clinical Research Network and having ≥2 weight measurements and 1 height measurement recorded in their EHR within the last 5 years. Recruitment strategies varied by site and included one or more of the following methods: (1) in-person recruitment by study staff from clinical sites, (2) US postal mail recruitment letters, (3) secure email, and (4) direct EHR recruitment through secure patient web portals. We used descriptive statistics to evaluate participant characteristics and proportion of patients recruited (ie, efficiency) by modality.

resultsThe total number of eligible patients from the 5 health systems was 5,051,187. Of these, 40,048 (0.8%) were invited to enter an EHR-based cohort study and 1085 were enrolled. Recruitment efficiency was highest for in-person recruitment (33.5%), followed by electronic messaging (2.9%), including email (2.9%) and EHR patient portal messages (2.9%). Overall, 779 (65.7%) patients were enrolled through electronic messaging, which also showed greater rates of recruitment of Black patients compared with the other strategies.

conclusionsWe recruited a total of 1085 patients from primary care and bariatric surgery settings using 4 recruitment strategies. The recruitment efficiency was 2.9% for email and EHR patient portals, with the majority of participants recruited electronically. This study can inform the design of future research studies using EHR-based recruitment.

Indexed as

Electronic Health RecordsPatient PortalsAdultCohort StudiesCross-Sectional StudiesHumansPatient Selectionbariatricclinical research networkcohortcohort study designefficiencyelectronic health recordeligibilityenrollmenthealth systemprimary careprocessrecruitmentrecruitment methodsresearchsurgery

Identifiers

PMID34042604
PMCPMC8193474
OpenAlexW3149192496

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.