Evidence map›Paper›PMID 34042560›Full record

Trial reportEmerging microbes & infections2021

Transcriptional signatures of human peripheral blood mononuclear cells can identify the risk of tuberculosis progression from latent infection among individuals with silicosis.

Qiao-Ling Ruan, Qing-Luan Yang, Yi-Xin Gao, Jing Wu, Si-Ran Lin, Jing-Yu Zhou, Ling-Yun Shao, Sen Wang, Qian-Qian Liu, Yan Gao and 2 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Emerging microbes & infections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02430259 (Effectiveness and Tolerability of Weekly Rifapentine/Isoniazid for 3 Months for Tuberculosis Preventive Treatment), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02430259 phase3completednot on this map

Effectiveness and Tolerability of Weekly Rifapentine/Isoniazid for 3 Months for Tuberculosis Preventive Treatment: A Randomized Controlled Study in China

TypeinterventionalSponsorHuashan HospitalRan2015 to 2018Enrolled566ConditionsSilicosis, TuberculosisArmsWeekly INH / RRT given by DOT
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Qiao-Ling RuanDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Qing-Luan YangDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Yi-Xin GaoDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Jing WuDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Si-Ran LinDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Jing-Yu ZhouDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Ling-Yun ShaoDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Sen WangDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Qian-Qian LiuDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Yan GaoDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Ning JiangDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Wen-Hong ZhangDepartment of Infectious Diseases, Huashan Hospital, School of Life Science, Fudan University, Shanghai, People's Republic of China.
Huashan Hospital · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CLINICAL

trial registrationwww.clinicaltrials.gov (NCT02430259).

Indexed as

AdolescentAdultAgedDisease ProgressionFemaleHumansLatent InfectionLeukocytes, MononuclearMaleMiddle AgedRisk FactorsSilicosisTuberculosisYoung Adultbiomarkerinterferon-gammalatent tuberculosis infectionperipheral blood mononuclear cellRNA sequencingTuberculosis

Identifiers

PMID34042560
PMCPMC8354161
OpenAlexW3164269777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.