Evidence map›Paper›PMID 34042251›Full record

ArticleJournal of applied clinical medical physics2021

Four-dimensional dose calculations for dynamic tumour tracking with a gimbal-mounted linear accelerator.

Emilie E Carpentier, Ronan L McDermott, Emma M Dunne, Marie-Laure A Camborde, Alanah M Bergman, Tania Karan, Mitchell C C Liu, Roy M K Ma, Ante Mestrovic

Open access · goldAbstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Four-dimensional treatment planning strategies for dynamic tumor tracking.Journal of applied clinical medical physics · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Emilie E CarpentierDepartment of Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada.
Ronan L McDermottRadiation Oncology, BC Cancer Vancouver, Vancouver, BC, Canada.
Emma M DunneRadiation Oncology, BC Cancer Vancouver, Vancouver, BC, Canada.
Marie-Laure A CambordeDepartment of Medical Physics, BC Cancer - Vancouver, Vancouver, BC, Canada.
Alanah M BergmanDepartment of Medical Physics, BC Cancer - Vancouver, Vancouver, BC, Canada.
Tania KaranDepartment of Medical Physics, BC Cancer - Vancouver, Vancouver, BC, Canada.
Mitchell C C LiuRadiation Oncology, BC Cancer Vancouver, Vancouver, BC, Canada.
Roy M K MaRadiation Oncology, BC Cancer Vancouver, Vancouver, BC, Canada.
Ante MestrovicDepartment of Medical Physics, BC Cancer - Vancouver, Vancouver, BC, Canada.
BC Cancer Agency · CASpinal Cord Injury BC · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this study we present a novel method for re-calculating a treatment plan on different respiratory phases by accurately modeling the panning and tilting beam motion during DTT (the "rotation method"). This method is used to re-calculate the dose distribution of a plan on multiple breathing phases to accurately assess the dosimetry.

methodssIMRT plans were optimized on a breath hold computed tomography (CT) image taken at exhale (BH

resultsIn total, 26 OARs were examined from 10 patients. When the dose was calculated on the inhale and exhale phases six OARs exceeded their dose limit, and when all 10 phases were used five OARs exceeded their limit.

conclusionDynamic tumor tracking plans optimized for a single respiratory phase leave an OAR vulnerable to exceeding its dose constraint during other respiratory phases. The rotation method accurately models the beam's geometry. Using deformable image registration to accumulate dose from all 10 breathing phases provides the most accurate results, however it is a time consuming procedure. Accumulating the dose from two extreme breathing phases (exhale and inhale) and weighting them properly provides accurate results while requiring less time. This approach should be used to confirm the safety of a DTT treatment plan prior to delivery.

Indexed as

Lung NeoplasmsNeoplasmsFour-Dimensional Computed TomographyHumansParticle AcceleratorsRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRespiration4D dose calculationdynamic tumor trackinggimballed linac system

Identifiers

PMID34042251
PMCPMC8200513
OpenAlexW3164192340

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.