Evidence map›Paper›PMID 34042247›Full record

ArticleDevelopmental dynamics : an official publication of the American Association of Anatomists2021

New techniques for creating parthenogenetic larvae of the sea urchin Lytechinus pictus for gene expression studies.

Victor D Vacquier, Amro Hamdoun

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Developmental dynamics : an official publication of the American Association of Anatomists, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Victor D VacquierCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.
Amro HamdounCenter for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, University of California San Diego, La Jolla, California, USA.ORCID 0000-0003-2568-048X
Scripps Institution of Oceanography · US

Funding

Identity, mechanisms and early life impacts of transporter interfering compoundsR01ES027921 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHANG, GEOFFREY A, HAMDOUN, AMRO M · 2018 to 2022
$3.0M
Molecular Mechanisms of Marine Organohalogen Bioaccumulation and NeurotoxicityR01ES030318 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMDOUN, AMRO M, PESSAH, ISAAC N · 2018 to 2022
$826k
NIEHS NIH HHS R01 ES027921NIEHS NIH HHS R01 ES030318
6 · The paper itself

Abstract

backgroundSea urchins are model organisms for studying the spatial-temporal control of gene activity during development. The Southern California species, Lytechinus pictus, has a sequenced genome and can be raised in the laboratory from egg to egg in 4 to 5 months.

resultsHere, we present new techniques for generating parthenogenetic larvae of this species and include a gallery of photomicrographs of morphologically abnormal larvae that could be used for transcriptomic analysis.

conclusionsComparison of gene expression in parthenogenotes to larvae produced by fertilization could provide novel insights into gene expression controls contributed by sperm in this important model organism. Knowledge gained from transcriptomics of sea urchin parthenogenotes could contribute to parthenogenetic studies of mammalian embryos.

Indexed as

Genetic TechniquesLytechinusAnimalsEmbryo, NonmammalianFemaleFertilizationGene Expression ProfilingGene Expression Regulation, DevelopmentalInventionsIonophoresLarvaMaleParthenogenesisSea UrchinsIonophoresembryoionophore activationlarvaeparthenogenesissea urchin

Identifiers

PMID34042247
PMCPMC8626522
OpenAlexW3165157109

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.