Evidence map›Paper›PMID 34042049›Full record

ReviewRheumatic diseases clinics of North America2021

Racial/Ethnic, Socioeconomic, and Geographic Disparities in the Epidemiology of Knee and Hip Osteoarthritis.

Leigh F Callahan, Rebecca J Cleveland, Kelli D Allen, Yvonne Golightly

Registry-linked trialAbstract readReview
In one paragraph

Review in Rheumatic diseases clinics of North America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07402291 (Comparative Effects of Mulligan's Pain Release Phenomenon and Kaltenborn Mobilizations on Pain, Range of Motion And Disability in Patients With Knee Osteoarthritis.), which is not on this map. Cited by 66 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07402291 nacompletednot on this mapstarted 2025, after this paper: background citation

Comparative Effects of Mulligan's Pain Release Phenomenon and Kaltenborn Mobilizations on Pain, Range of Motion And Disability in Patients With Knee Osteoarthritis.

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2025Enrolled44ConditionsKnee OsteoarthritisArmsMulligan's pain release phenomenon, Kaltenborn mobilization with traction
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. [The role and mechanism of chemokine network in promoting osteoarthritis progression by regulating synovial macrophage heterogeneity].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Review
  8. Prevalence and occupational risk of hip osteoarthritis and rotator cuff lesions - claims data analysis.International journal of occupational medicine and environmental health · 2026
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. The Impact of the Area Deprivation Index on Knee and Hip Health.Journal of racial and ethnic health disparities · 2026
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Leigh F CallahanSchool of Medicine, Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3330 Thurston Building, CB 7280, Chapel Hill, NC 27599, USA. Electronic address: leigh_callahan@med.unc.edu.
Rebecca J ClevelandSchool of Medicine, Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3330 Thurston Building, CB 7280, Chapel Hill, NC 27599, USA.
Kelli D AllenSchool of Medicine, Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3330 Thurston Building, CB 7280, Chapel Hill, NC 27599, USA; Center of Innovation to Accelerate Discovery and Practice Transformation, VA Healthcare System, Durham, NC, USA.
Yvonne GolightlySchool of Medicine, Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, 3330 Thurston Building, CB 7280, Chapel Hill, NC 27599, USA; Gillings School of Global Public Health, University of North Carolina at Chapel Hill, 3300 Thurston Building CB 7280, Chapel Hill, NC 27599-7280, USA.

Funding

UNC Core Center for Clinical ResearchP30AR072580 · NIAMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LEIGH Fleming CALLAHAN, Amanda E Nelson · 2019 to 2026
$6.1M
NIAMS NIH HHS P30 AR072580
6 · The paper itself

Abstract

It is estimated that 32.5 million US adults have clinical osteoarthritis (OA), with the most common sites being knee and hip. OA is associated with substantial individual and societal costs. Race/ethnicity, socioeconomic status (SES), and geographic variations in the prevalence of knee and hip OA are well established around the world. In addition, clinical outcomes associated with hip and knee OA differ according to race/ethnicity, SES, and geography. This variation is likely multifactorial and may also reflect country-specific differences in health care systems. The interplay between different factors, such as geography, SES, and race/ethnicity, is difficult to study.

Indexed as

Osteoarthritis, HipOsteoarthritis, KneeAdultEthnicityHumansSocioeconomic FactorsGeographic disparitiesHip osteoarthritisKnee osteoarthritisRacial/ethnic disparitiesSocioeconomic status

Identifiers

PMID34042049
PMCPMC8248516

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.