Evidence map›Paper›PMID 34042048›Full record

ArticleeLife2021

RSC primes the quiescent genome for hypertranscription upon cell-cycle re-entry.

Christine E Cucinotta, Rachel H Dell, Keean Ca Braceros, Toshio Tsukiyama

Abstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Microbial life in slow and stopped lanes.Trends in microbiology · 2024
    Review
  10. Article
  11. Quiescence inAnnual review of genetics · 2022
    Review
  12. FOXG1 Contributes Adult Hippocampal Neurogenesis in Mice.International journal of molecular sciences · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Quiescence Through the Prism of Evolution.Frontiers in cell and developmental biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christine E CucinottaBasic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, United States.ORCID 0000-0002-9644-3126
Rachel H DellBasic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, United States.
Keean Ca BracerosBasic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, United States.
Toshio TsukiyamaBasic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, United States.ORCID 0000-0001-6478-6207

Funding

Chromosome Metabolism and Cancer Training GrantT32CA009657 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI EISENMAN, ROBERT NEIL · 1991 to 2020
$7.6M
Molecular mechanisms and functions of global chromatin controlR35GM139429 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TOSHIO TSUKIYAMA · 2021 to 2026
$4.6M
Mechanisms and functions of chromatin regulation for cell-cycle controlR01GM111428 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI TSUKIYAMA, TOSHIO · 2015 to 2020
$2.4M
Mechanisms of massive genome reactivation during quiescence exitF32GM131554 · NIGMS · FRED HUTCHINSON CANCER RESEARCH CENTER · PI CUCINOTTA, CHRISTINE E · 2019 to 2020
$127k
NCI NIH HHS T32 CA009657NIGMS NIH HHS F32 GM131554NIGMS NIH HHS R01 GM111428NIGMS NIH HHS R35 GM139429
6 · The paper itself

Abstract

Quiescence is a reversible G

Indexed as

Cell CycleCellular SenescenceGene Expression Regulation, FungalGenome, FungalTranscription, GeneticChromatin Assembly and DisassemblyDNA-Binding ProteinsNucleosomesRNA Polymerase IISaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTime FactorsTranscription FactorsDNA-Binding ProteinsNucleosomesRNA Polymerase IIRSC complex, S cerevisiaeSaccharomyces cerevisiae ProteinsTranscription Factorschromatinchromatin remodelingchromosomesgene expressionquiescencequiescence exitRSCS. cerevisiaetranscription

Identifiers

PMID34042048
PMCPMC8186906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.