Evidence map›Paper›PMID 34041873›Full record

ArticleHua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology2021

Protective effect of low-level laser irradiation on lipopolysaccharide-mediated inflammatory injury of human periodontal ligament fibroblasts.

Xiao-Lan Jin, Ya-Nan Zhang, Cheng-Rui Sun, Zhao-Hui Zou

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Xiao-Lan JinDept. of Stomatology, Tianjin Jinnan Hospital, Tianjin 300350, China.
Ya-Nan ZhangDept. of Stomatology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300192, China.
Cheng-Rui SunDept. of Stomatology, Tianjin Jinnan Hospital, Tianjin 300350, China.
Zhao-Hui ZouDept. of Endodontics Third Room, School of Stomatology, Tianjin Medical University, Tianjin 300070, China.
Tianjin Stomatological Hospital · CNTianjin Medical University · CNTianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo study the effect and mechanism of low-level laser irradiation (LLLI) on lipopolysaccharide (LPS)-induced inflammatory injury of human periodontal ligament fibroblasts (hPDLFs).

methodshPDLFs were inoculated into well plates and randomly divided into the normal group, LPS group, and LPS+LLLI group. The cells in the normal group were cultured in conventional medium. The hPDLFs in the LPS and LPS+LLLI groups were cultured in RPMI1640 medium containing 1 mg·L

resultsCompared with the normal group, the LPS group showed increased apoptosis rate of hPDLFs and intracellular free Ca

conclusionsLLLI has a protective effect on the inflammatory injury of hPDLFs induced by LPS, and the effect is most obvious when the irradiation intensity is 4 J·cm

Indexed as

LipopolysaccharidesPeriodontal LigamentCells, CulturedFibroblastsHumansInterleukin-1betaLasersTumor Necrosis Factor-alphaInterleukin-1betaLipopolysaccharidesTumor Necrosis Factor-alphaeffecthuman periodontal ligament fibroblastsinflammatory injurylipopolysaccharidelow-level laser irradiation

Identifiers

PMID34041873
PMCPMC8218258
OpenAlexW3165863379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.