Evidence map›Paper›PMID 34041717›Full record

ReviewMolecular biotechnology2021

Advances and Perspectives in the Application of CRISPR-Cas9 in Livestock.

Abdul Jabbar, Farheen Zulfiqar, Mahnoor Mahnoor, Nadia Mushtaq, Muhammad Hamza Zaman, Anum Salah Ud Din, Musarrat Abbas Khan, Hafiz Ishfaq Ahmad

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Climate resilience in goats: a comprehensive review of the genetic basis for adaptation to varied climatic conditions.Mammalian genome : official journal of the International Mammalian Genome Society · 2025
    Review
  5. Review
  6. Optimization of CRISPR/Cas9 Gene Editing System in Sheep (International journal of molecular sciences · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. CRISPR: Beyond the Excitement.Journal of bioethical inquiry · 2024
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abdul JabbarDepartment of Clinical Medicine, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, 54000, Punjab, Pakistan.ORCID https://orcid.org/0000-0003-4528-8389
Farheen ZulfiqarDepartment of Food Science and Human Nutrition, Faculty of Bio Science, University of Veterinary and Animal Sciences, Lahore, 54000, Punjab, Pakistan.ORCID https://orcid.org/0000-0002-0509-9519
Mahnoor MahnoorDepartment of Food Science and Human Nutrition, Faculty of Bio Science, University of Veterinary and Animal Sciences, Lahore, 54000, Punjab, Pakistan.ORCID https://orcid.org/0000-0003-2163-075X
Nadia MushtaqDepartment of Biological Sciences, Faculty of Fisheries and Wildlife, University of Veterinary and Animal Sciences, Lahore, 54000, Punjab, Pakistan.ORCID https://orcid.org/0000-0002-3101-411X
Muhammad Hamza ZamanCollege of Earth and Environmental Sciences, University of the Punjab, Lahore, 54590, Punjab, Pakistan.ORCID https://orcid.org/0000-0003-3133-2983
Anum Salah Ud DinCollege of Earth and Environmental Sciences, University of the Punjab, Lahore, 54590, Punjab, Pakistan.ORCID https://orcid.org/0000-0002-4459-1813
Musarrat Abbas KhanDepartment of Animal Breeding and Genetics, Faculty of Veterinary and Animal Science, The Islamia University, Bahawalpur, Pakistan.
Hafiz Ishfaq AhmadDepartment of Animal Breeding and Genetics, University of Veterinary and Animal Sciences, Ravi Campus, Pattoki, Punjab, Pakistan. ishfaq.ahmad@uvas.edu.pk.ORCID http://orcid.org/0000-0002-9206-2596

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sophistication and revolution in genome editing and manipulation have revolutionized livestock by harvesting essential biotechnological products such as drugs, proteins, and serum. It laid down areas for the large production of transgenic food, resistance against certain diseases such as mastitis, and large production of milk and leaner meat. Nowadays, the increasing demand for animal food and protein is fulfilled using genome-editing technologies. The recent genome-editing techniques have overcome the earlier methods of animal reproduction, such as cloning and artificial embryo transfer. The genome of animals now is modified using the recent alteration techniques such as ZFNs, TALENS technique, and clustered regularly interspaced short palindromic repeats/Cas9 (CRISPR-Cas9) system. The literature was illustrated for identifying the researchers to address the advances and perspectives in the application of Cas9 in Livestock. Cas9 is considered better than the previously identified techniques in livestock because of the production of resilience against diseases, improvement of reproductive traits, and animal production to act as a model biomedical research.

Indexed as

Animals, Genetically ModifiedCRISPR-Cas SystemsAnimalsCattleFemaleGene EditingGenomeGoatsLivestockMastitisMeatMilkOrgan TransplantationPolymerase Chain ReactionSheep, DomesticSwineTranscription Activator-Like Effector NucleasesCRISPRGenetic manipulationLivestock

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.