Evidence map›Paper›PMID 34041625›Full record

ArticleAnnals of surgical oncology2021

Does Cardiopulmonary Testing Help Predict Long-Term Survival After Esophagectomy?

Jakub Chmelo, Rachel A Khaw, Rhona C F Sinclair, Maziar Navidi, Alexander W Phillips

Open access · hybridAbstract read
In one paragraph

Article in Annals of surgical oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Measurement and optimization of perioperative risk among patients undergoing surgery for esophageal cancer.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2024
    Article
  5. The impact of age on long-term survival following gastrectomy for gastric cancer.Annals of the Royal College of Surgeons of England · 2023
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jakub ChmeloNorthern Oesophagogastric Unit, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.
Rachel A KhawNorthern Oesophagogastric Unit, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.
Rhona C F SinclairDepartment of Anaesthesia and Critical Care Medicine, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.
Maziar NavidiNorthern Oesophagogastric Unit, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.
Alexander W PhillipsNorthern Oesophagogastric Unit, Royal Victoria Infirmary, Newcastle Upon Tyne, UK. awphillips@doctors.net.uk.ORCID http://orcid.org/0000-0001-9826-3949
Royal Victoria Infirmary · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEsophagectomy is associated with a high rate of morbidity and mortality. Preoperative cardiopulmonary fitness has been correlated with outcomes of major surgery. Variables derived from cardiopulmonary exercise testing (CPET) have been associated with postoperative outcomes. It is unclear whether preoperative cardiorespiratory fitness of patients undergoing esophagectomy is associated with long-term survival. This study aimed to evaluate whether any of the CPET variables routinely derived from patients with esophageal cancer may aid in predicting long-term survival after esophagectomy.

methodsPatients undergoing CPET followed by trans-thoracic esophagectomy for esophageal cancer with curative intent between January 2013 and January 2017 from single high-volume center were retrospectively analyzed. The relationship between predictive co-variables, including CPET variables and survival, was studied with a Cox proportional hazard model. Receiver operation curve (ROC) analysis was performed to find cutoff values for CPET variables predictive of 3-year survival.

resultsThe study analyzed 313 patients. The ventilatory equivalent for carbon dioxide (VE/VCO

conclusionsA high VE/VCO

Indexed as

Anaerobic ThresholdEsophagectomyExercise TestHumansPredictive Value of TestsRetrospective Studies

Identifiers

PMID34041625
PMCPMC8519940
OpenAlexW3165728135

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.