ArticleInternational orthopaedics2022
Diagnostic value of necrotic lesion boundary in bone collapse of femoral head osteonecrosis.
Article in International orthopaedics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- A delphi-based model for prognosis of femoral head collapse in osteonecrosis: a multi-factorial approach.Journal of orthopaedic surgery and research · 2024Pooled it
- Predictive value of clinical features and CT radiomics in the efficacy of hip preservation surgery with fibula allograft.Journal of orthopaedic surgery and research · 2023Trial
- Association of anterior necrotic boundary location with collapse progression in symptomatic osteonecrosis of the femoral head: analysis of ARCO 2021 type 2 lesions.BMC musculoskeletal disorders · 2026Article
- X-ray based radiomics machine learning models for predicting collapse of early-stage osteonecrosis of femoral head.Scientific reports · 2025Article
- Risk assessment for femoral head collapse in osteonecrosis utilizing MRI-derived large lesion ratio: a retrospective cohort study.BMC musculoskeletal disorders · 2024Article
- Factors related to collapse progression in Japanese Investigation Committee classification type B osteonecrosis of the femoral head.International orthopaedics · 2024Article
- The Preserved Thickness Ratio of the Femoral Head Contributes to the Collapse Predictor of Osteonecrosis.Orthopaedic surgery · 2024Article
- Analysis of the natural collapse course of non-traumatic osteonecrosis of the femoral head based on the matrix model.Journal of orthopaedic surgery and research · 2024Article
- Revisiting prediction of collapse in hip osteonecrosis with artificial intelligence and machine learning: a new approach for quantifying and ranking the contribution and association of factors for collapse.International orthopaedics · 2023Article
- Evaluation of the predictive values of collapse and necrotic lesion boundary for osteonecrosis of the femoral head prognosis.Frontiers in endocrinology · 2023Article
- Clinical Outcome of Surgical Hip Dislocation Combined with Impacting Bone Grafts and Implanting Iliac Bone Flaps in the Treatment of Osteonecrosis of the Femoral Head: A Mid-term Retrospective Study.Orthopaedic surgery · 2022Article
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Authors and funding
14 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOur research developed a novel approach to quantitatively evaluate the boundary of necrotic lesions in osteonecrosis of the femoral head (ONFH) and to explore its diagnostic value in predicting bone collapse of the femoral head.
methodsA retrospective cross-sectional study was conducted in our institution, and 146 hips (121 cases) identified as ONFH were recruited. The anterior and lateral boundaries of each enrolled subject were measured in standard anteroposterior (AP) view and frog-leg (FL) view of plain radiographic images, the intact rate of which was then calculated and presented as the anteroposterior view intact ratio (APIR) and frog-leg view intact ratio (FLIR), respectively. Univariate and multivariate logistic regression analyses were performed to identify risk factors for collapse. A receiver operating characteristic (ROC) curve analysis was performed to determine the sensitivity, specificity and cutoff value of the APIR and FLIR. A Kaplan-Meier (K-M) analysis was applied to calculate the survival rate of the femoral head, and bone collapse of the femoral head was regarded as the endpoint.
resultsFemoral head collapse was observed in 61 hips during the follow-up period. Patients with or without femoral head collapse were categorized into the collapse group and non-collapse group, respectively. The mean follow-up time was 3.7 years (2-9) for the collapse group and 7.7 years (5-20) for the non-collapse group. Univariate and multivariate logistic regression analysis and ROC analysis showed that APIR (< 25.61%) and FLIR (< 24.43%) were significantly associated with femoral head collapse. The K-M survival curves indicated that the overall survival rate of APIR (≥ 25.61%) was 94.8% at 7.5 years and 76.6% at 10 years, while that of FLIR (≥ 24.43%) was 87.3% at 7.5 years and ten years.
conclusionThe present study demonstrates that APIR and FLIR are of high diagnostic value in the early and middle stages of ONFH. APIR and FLIR can be used to predict the occurrence of femoral head collapse in patients with JIC classification types B and C1. The measurement of these two parameters in plain radiography images may contribute to the selection of a proper hip preservation strategy.
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