Evidence map›Paper›PMID 34041498›Full record

ArticleJACC. Case reports2021

Allogeneic Mesenchymal Stromal Cell Injection to Alleviate Ischemic Heart Failure Following Arterial Switch Operation.

Filippo Rapetto, Demetris Taliotis, Qiang Chen, Iakovos Ttofi, Dominga Iacobazzi, Paolo Madeddu, Serban C Stoica, Ben Weil, Mark W Lowdell, Massimo Caputo

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Filippo RapettoDepartment of Cardiac Surgery, Bristol Heart Institute and Bristol Royal Hospital for Children, Bristol, United Kingdom.
Demetris TaliotisDepartment of Cardiology, Bristol Heart Institute and Bristol Royal Hospital for Children, Bristol, United Kingdom.
Qiang ChenDepartment of Cardiac Surgery, Bristol Heart Institute and Bristol Royal Hospital for Children, Bristol, United Kingdom.
Iakovos TtofiDepartment of Cardiac Surgery, Bristol Heart Institute and Bristol Royal Hospital for Children, Bristol, United Kingdom.
Dominga IacobazziTranslational Health Sciences, University of Bristol, Bristol, United Kingdom.
Paolo MadedduTranslational Health Sciences, University of Bristol, Bristol, United Kingdom.
Serban C StoicaDepartment of Cardiac Surgery, Bristol Heart Institute and Bristol Royal Hospital for Children, Bristol, United Kingdom.
Ben WeilCentre for Cell, Gene & Tissue Therapeutics, Royal Free London NHS Foundation Trust, London, United Kingdom.
Mark W LowdellCentre for Cell, Gene & Tissue Therapeutics, Royal Free London NHS Foundation Trust, London, United Kingdom.
Massimo CaputoDepartment of Cardiac Surgery, Bristol Heart Institute and Bristol Royal Hospital for Children, Bristol, United Kingdom.
Bristol Royal Hospital for Children · GBUniversity of Bristol · GBRoyal Free London NHS Foundation Trust · GB

Funding

British Heart Foundation CH/17/1/32804British Heart Foundation PG/15/33/31394
6 · The paper itself

Abstract

Cell therapy is a promising tool to prevent and treat heart failure in congenital heart disease. We report the first case of intramyocardial injection of allogeneic mesenchymal stromal cells as rescue therapy in a neonate with ischemic heart failure following arterial switch procedure for isolated transposition of the great arteries. (

Indexed as

acute heart failureCHD, congenital heart diseasecoronary vessel anomalyFAC, fractional area changeGLS, global longitudinal strainLCA, left coronary arteryLV, left ventricularMSC, mesenchymal stromal celltransposition of the great arteries

Identifiers

PMID34041498
PMCPMC8134060
OpenAlexW3162695225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.