Evidence map›Paper›PMID 34041411›Full record

ArticleHeliyon2021

Effects of supplementation with kombucha and green banana flour on Wistar rats fed with a cafeteria diet.

Marianela Andrea Díaz Urrutia, Amanda Gemelli Ramos, Rafaela Beatriz Menegusso, Rafael Dewes Lenz, Mateus Gemelli Ramos, Adriana Gadioli Tarone, Cinthia Baú Betim Cazarin, Solange Maria Cottica, Sóstenez Alexandre Vessaro da Silva, Daniela Miotto Bernardi

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Kombucha: Challenges for Health and Mental Health.Foods (Basel, Switzerland) · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Marianela Andrea Díaz UrrutiaCentro Universitário Fundação Assis Gurgacz, Avenida da Torres, 500, Cascavel, PR, CEP: 85806 - 096, Brazil.
Amanda Gemelli RamosCentro Universitário Fundação Assis Gurgacz, Avenida da Torres, 500, Cascavel, PR, CEP: 85806 - 096, Brazil.
Rafaela Beatriz MenegussoCentro Universitário Fundação Assis Gurgacz, Avenida da Torres, 500, Cascavel, PR, CEP: 85806 - 096, Brazil.
Rafael Dewes LenzCentro Universitário Fundação Assis Gurgacz, Avenida da Torres, 500, Cascavel, PR, CEP: 85806 - 096, Brazil.
Mateus Gemelli RamosFederal University of Parana, Rua XV de Novembro, 1299, Centro, Curitiba, PR, CEP: 80060-000, Brazil.
Adriana Gadioli TaroneUniversity of Campinas, Cidade Universitária Zeferino Vaz, Rua Monteiro Lobato, 80, Campinas, SP, Caixa Postal: 6121, CEP: 13.083-862, Brazil.
Cinthia Baú Betim CazarinUniversity of Campinas, Cidade Universitária Zeferino Vaz, Rua Monteiro Lobato, 80, Campinas, SP, Caixa Postal: 6121, CEP: 13.083-862, Brazil.
Solange Maria CotticaFederal Technological University of Parana, Rua Cristo Rei, 19, Vila Becker, Toledo, PR, CEP: 85902-490, Brazil.
Sóstenez Alexandre Vessaro da SilvaCentro Universitário Fundação Assis Gurgacz, Avenida da Torres, 500, Cascavel, PR, CEP: 85806 - 096, Brazil.
Daniela Miotto BernardiCentro Universitário Fundação Assis Gurgacz, Avenida da Torres, 500, Cascavel, PR, CEP: 85806 - 096, Brazil.
Centro Universitário Fundação Assis Gurgacz · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Federal do Paraná · BRUniversidade Tecnológica Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWith the increase of chronic diseases as a consequence of the population's eating habits, there is also a growing interest in foods rich in bioactive compounds capable of mitigating these diseases. Thus, this study aimed to evaluate the effects of supplementation with kombucha and green banana flour (GBF) on Wistar rats fed with cafeteria diet (CAF).

methodsThe animals were randomized into five groups of seven animals each, which were fed with the following diets: Treatment 1 (T1): Control treatment/commercial feed; Treatment 2 (T2): cafeteria diet (CAF); Treatment 3 (T3): CAF + kombucha; Treatment 4 (T4): CAF + green banana flour (GBF); Treatment 5 (T5): CAF + GBF + kombucha. Daily weight gain, daily food consumption, feed conversion, blood glucose, total cholesterol and fractions, triglycerides, liver enzymes, antioxidant activity, and body composition were evaluated.

resultsT5 presented lower feed intake and less weight gain. Liver histology revealed vacuolization in all treatments except T1, which was confirmed by the results of liver enzymes. There was no increase in blood glucose, and changes were observed in the lipid profile of the animals. T1 had the lowest body fat and the highest protein levels. Differences were observed for the antioxidant capacity in the liver of animals among treatments.

conclusionThe intake of cafeteria diet altered the lipid and liver profile of the animals and the consumption of kombucha and GBF did not prevent these changes. The high polyphenols level of kombucha did not exert a hepatoprotective effect as an antioxidant. However, this supplementation generated greater satiety in the animals, leading to less weight gain until the end of the experiment.

Indexed as

Antioxidant activityCafeteria dietFunctional foodsHepatic steatosisHypercaloric diet

Identifiers

PMID34041411
PMCPMC8144004
OpenAlexW3165579306

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.