Evidence map›Paper›PMID 34041299›Full record

ArticleBioMed research international2021

Impact of Albendazole on Cytokine and Chemokine Response Profiles in

Jing Wu, Hai-Zhang Ma, Shadike Apaer, Nuerzatijiang Anweier, Qi Zeng, Xiafukati Fulati, Tao Li, Jin-Ming Zhao, Hao Wen, Tuerhongjiang Tuxun

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Evaluation of the prophylactic and therapeutic effects of selenium and vitamin E on the muscular phase of experimentalJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Jing WuState Key Laboratory of Pathogenesis, Prevention, Treatment of High Incidence Diseases in Central Asia, Xinjiang Medical University, Urumqi 830054, China.
Hai-Zhang MaDepartment of Organ Transplant, Qilu Hospital of Shandong University, Jinan 250012, China.
Shadike ApaerState Key Laboratory of Pathogenesis, Prevention, Treatment of High Incidence Diseases in Central Asia, Xinjiang Medical University, Urumqi 830054, China.
Nuerzatijiang AnweierDepartment of Liver & Laparoscopic Surgery, Digestive & Vascular Surgery Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Qi ZengDepartment of Liver & Laparoscopic Surgery, Digestive & Vascular Surgery Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Xiafukati FulatiDepartment of Liver & Laparoscopic Surgery, Digestive & Vascular Surgery Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Tao LiDepartment of Liver & Laparoscopic Surgery, Digestive & Vascular Surgery Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Jin-Ming ZhaoDepartment of Liver & Laparoscopic Surgery, Digestive & Vascular Surgery Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Hao WenState Key Laboratory of Pathogenesis, Prevention, Treatment of High Incidence Diseases in Central Asia, Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0001-7144-220X
Tuerhongjiang TuxunState Key Laboratory of Pathogenesis, Prevention, Treatment of High Incidence Diseases in Central Asia, Xinjiang Medical University, Urumqi 830054, China.ORCID https://orcid.org/0000-0003-2978-1472
Xinjiang Medical University · CNQilu Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAlveolar echinococcosis (AE) is a zoonosis caused by the larval stage of the metacestode

methodsMice were inoculated with

resultsThe hepatic AE lesion was confirmed by ultrasound examination resulting in a successful rate of 70%. Among the 17 cytokines and chemokines detected, plasma levels of IL-23 were significantly higher in

conclusionAlbendazole administration influenced the balance of immune response and promotes the secretion of proinflammatory factors which is beneficial to parasite clearance. IL-23 seems to be associated with the successful albendazole treatment in mice with

Indexed as

AlbendazoleAnimalsChemokinesCytokinesDisease Models, AnimalEchinococcosisEchinococcosis, HepaticEchinococcus multilocularisFemaleHumansImmunityInterleukin-23MiceMice, Inbred BALB CTh17 CellsTh1 CellsAlbendazoleChemokinesCytokinesInterleukin-23

Identifiers

PMID34041299
PMCPMC8121589
OpenAlexW3157444321

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.