ArticleFrontiers in molecular biosciences2021
Large-Scale Recombinant Production of the SARS-CoV-2 Proteome for High-Throughput and Structural Biology Applications.
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Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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34citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
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34 citing papers in PubMed, 53 citations in OpenAlex.
- Structural Features of a Tiny Viral Protein, ORF7b of SARS-CoV-2.International journal of molecular sciences · 2026Article
- Peptidomimetic α,β-Unsaturated Ethyl Esters Are Irreversible Inactivators of Human Cathepsin L and Are Potent Inhibitors of SARS-CoV-2 in Cellular Models of COVID-19.Journal of medicinal chemistry · 2026Article
- The DMV pore-forming TM2-Y region of SARS-CoV-2 nsp3 exhibits structural conservation beyond the coronavirus family.Journal of virology · 2026Article
- Peptide ligands to explore interactions with intrinsically disordered multidomain proteins: the case of SARS-CoV-2 nucleocapsid protein.Scientific reports · 2026Article
- How does NMR support SARS-CoV-2 protein-ligand interaction studies?Analytical and bioanalytical chemistry · 2026Review
- Integrative In Silico and In Vitro Screening of Low Molecular Weight Compounds Targeting SARS-CoV-2 RNA Elements.Chembiochem : a European journal of chemical biology · 2025Article
- Support Vector Machine Identification of Small Molecule Binders to an Understudied Allosteric Site of SARS-CoV-2 Mpro for Next-Generation PROTAC-Based Therapeutics.Archiv der Pharmazie · 2025Article
- NMR screening of low molecular weight inhibitors targeting the papain-like protease (PLPro) of SARS-CoV-2.FEBS open bio · 2025Article
- Structural heterogeneity and dynamics in the apical stem loop of s2m from SARS-CoV-2 Delta by an integrative NMR spectroscopy and MD simulation approach.Nucleic acids research · 2025Article
- Revealing the Potential of a Chimaera: a Peptide-Peptide Nucleic Acid Molecule Designed To Interact with the SARS-CoV-2 Nucleocapsid Protein.Angewandte Chemie (International ed. in English) · 2025Article
- A core network in the SARS-CoV-2 nucleocapsid NTD mediates structural integrity and selective RNA-binding.Nature communications · 2024Article
- Analysis of the structure and interactions of the SARS-CoV-2 ORF7b accessory protein.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Oligomeric assembly of the C-terminal and transmembrane region of SARS-CoV-2 nsp3.Journal of virology · 2024Article
- Targeting the Main Protease (MACS chemical biology · 2024Article
- Cell-Free Synthesis of Bunyavirales Proteins in View of Their Structural Characterization by Nuclear Magnetic Resonance.Methods in molecular biology (Clifton, N.J.) · 2024Article
- The preference signature of the SARS-CoV-2 Nucleocapsid NTD for its 5'-genomic RNA elements.Nature communications · 2023Article
- Biochemical and HDX Mass Spectral Characterization of the SARS-CoV-2 Nsp1 Protein.Biochemistry · 2023Article
- A hybrid structure determination approach to investigate the druggability of the nucleocapsid protein of SARS-CoV-2.Nucleic acids research · 2023Article
- Identification of Natural Products Inhibiting SARS-CoV-2 by Targeting Viral Proteases: A Combined in Silico and in Vitro Approach.Journal of natural products · 2023Article
- Crystal structure of the CoV-Y domain of SARS-CoV-2 nonstructural protein 3.Scientific reports · 2023Article
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Authors and funding
129 authors at 20 institutions in 9 countries.
Nadide AltincekicInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Sophie Marianne KornCenter of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Frankfurt am Main, Germany.
Nusrat Shahin QureshiInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Marie DujardinMolecular Microbiology and Structural Biochemistry, UMR 5086, CNRS/Lyon University, Lyon, France.
Martí Ninot-PedrosaMolecular Microbiology and Structural Biochemistry, UMR 5086, CNRS/Lyon University, Lyon, France.
Rupert AbeleInstitute for Biochemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.
Marie Jose Abi SaadSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Caterina AlfanoStructural Biology and Biophysics Unit, Fondazione Ri.MED, Palermo, Italy.
Fabio C L AlmeidaNational Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Islam AlshamlehInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Gisele Cardoso de AmorimNational Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Thomas K AndersonInstitute for Molecular Virology, University of Wisconsin-Madison, Madison, WI, United States.
Cristiane D AnobomNational Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Chelsea AnormaDepartment of Chemistry, University of California, Irvine, CA, United States.
Jasleen Kaur BainsInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Adriaan BaxLCP, NIDDK, NIH, Bethesda, MD, United States.
Martin BlackledgeUniv. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Julius BlecharInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Anja BöckmannMolecular Microbiology and Structural Biochemistry, UMR 5086, CNRS/Lyon University, Lyon, France.
Louis BrigandatMolecular Microbiology and Structural Biochemistry, UMR 5086, CNRS/Lyon University, Lyon, France.
Anna BulaLatvian Institute of Organic Synthesis, Riga, Latvia.
Matthias BütikoferSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Aldo R Camacho-ZarcoUniv. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Teresa CarlomagnoBMWZ and Institute of Organic Chemistry, Leibniz University Hannover, Hannover, Germany.
Icaro Putinhon CarusoNational Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Betül CeylanInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Apirat ChaikuadInstitute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.
Feixia ChuDepartment of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States.
Laura ColeMolecular Microbiology and Structural Biochemistry, UMR 5086, CNRS/Lyon University, Lyon, France.
Marquise G CrosbyDepartment of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States.
Vanessa de JesusInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Karthikeyan DhamotharanCenter of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Frankfurt am Main, Germany.
Isabella C FelliMagnetic Resonance Centre (CERM), University of Florence, Sesto Fiorentino, Italy.
Jan FernerInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Yanick FleischmannSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Marie-Laure FogeronMolecular Microbiology and Structural Biochemistry, UMR 5086, CNRS/Lyon University, Lyon, France.
Nikolaos K FourkiotisDepartment of Pharmacy, University of Patras, Patras, Greece.
Christin FuksInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Boris FürtigInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Angelo GalloDepartment of Pharmacy, University of Patras, Patras, Greece.
Santosh L GandeInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Juan Atilio GerezSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Dhiman GhoshSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Francisco Gomes-NetoNational Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Oksana GorbatyukDepartment of Molecular Biology and Biophysics, UConn Health, Farmington, CT, United States.
Serafima GusevaUniv. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Carolin HackerSignals GmbH & Co. KG, Frankfurt am Main, Germany.
Sabine HäfnerLeibniz Institute on Aging-Fritz Lipmann Institute (FLI), Jena, Germany.
Bing HaoDepartment of Molecular Biology and Biophysics, UConn Health, Farmington, CT, United States.
Bruno HargittayInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
K Henzler-WildmanInstitute for Molecular Virology, University of Wisconsin-Madison, Madison, WI, United States.
Jeffrey C HochDepartment of Molecular Biology and Biophysics, UConn Health, Farmington, CT, United States.
Katharina F HohmannInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Marie T HutchisonInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Kristaps JaudzemsLatvian Institute of Organic Synthesis, Riga, Latvia.
Katarina JovićDepartment of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States.
Janina KaderliSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Gints KalniņšLatvian Biomedical Research and Study Centre, Riga, Latvia.
Iveta KaņepeLatvian Institute of Organic Synthesis, Riga, Latvia.
Robert N KirchdoerferInstitute for Molecular Virology, University of Wisconsin-Madison, Madison, WI, United States.
John KirkpatrickBMWZ and Institute of Organic Chemistry, Leibniz University Hannover, Hannover, Germany.
Stefan KnappInstitute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.
Robin KrishnathasInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Felicitas KutzInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Susanne Zur LageGroup of NMR-Based Structural Chemistry, Helmholtz Centre for Infection Research, Braunschweig, Germany.
Roderick LambertzInstitute for Molecular Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Andras LangLeibniz Institute on Aging-Fritz Lipmann Institute (FLI), Jena, Germany.
Douglas Laurents"Rocasolano" Institute for Physical Chemistry (IQFR), Spanish National Research Council (CSIC), Madrid, Spain.
Lauriane LecoqMolecular Microbiology and Structural Biochemistry, UMR 5086, CNRS/Lyon University, Lyon, France.
Verena LinhardInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Frank LöhrCenter of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Frankfurt am Main, Germany.
Anas MalkiUniv. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Luiza Mamigonian BessaUniv. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Rachel W MartinDepartment of Chemistry, University of California, Irvine, CA, United States.
Tobias MatzelInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Damien MaurinUniv. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Seth W McNuttDepartment of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States.
Nathane Cunha Mebus-AntunesNational Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Beat H MeierSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Nathalie MeiserInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Miguel Mompeán"Rocasolano" Institute for Physical Chemistry (IQFR), Spanish National Research Council (CSIC), Madrid, Spain.
Elisa MonacaStructural Biology and Biophysics Unit, Fondazione Ri.MED, Palermo, Italy.
Roland MontserretMolecular Microbiology and Structural Biochemistry, UMR 5086, CNRS/Lyon University, Lyon, France.
Laura Mariño PerezUniv. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Celine MoserIBG-4, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Claudia Muhle-GollIBG-4, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Thais Cristtina Neves-MartinsNational Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Xiamonin NiInstitute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt am Main, Germany.
Brenna Norton-BakerDepartment of Chemistry, University of California, Irvine, CA, United States.
Roberta PierattelliMagnetic Resonance Centre (CERM), University of Florence, Sesto Fiorentino, Italy.
Letizia PontorieroMagnetic Resonance Centre (CERM), University of Florence, Sesto Fiorentino, Italy.
Yulia PustovalovaDepartment of Molecular Biology and Biophysics, UConn Health, Farmington, CT, United States.
Oliver OhlenschlägerLeibniz Institute on Aging-Fritz Lipmann Institute (FLI), Jena, Germany.
Julien OrtsSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Andrea T Da PoianInstitute of Medical Biochemistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Dennis J PyperInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Christian RichterInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Roland RiekSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Chad M RienstraDepartment of Biochemistry and National Magnetic Resonance Facility at Madison, University of Wisconsin-Madison, Madison, WI, United States.
Angus RobertsonLCP, NIDDK, NIH, Bethesda, MD, United States.
Anderson S PinheiroNational Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Raffaele SabbatellaStructural Biology and Biophysics Unit, Fondazione Ri.MED, Palermo, Italy.
Nicola SalviUniv. Grenoble Alpes, CNRS, CEA, IBS, Grenoble, France.
Krishna SaxenaInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Linda SchulteInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Marco SchiavinaMagnetic Resonance Centre (CERM), University of Florence, Sesto Fiorentino, Italy.
Harald SchwalbeInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Mara SilberIBG-4, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Marcius da Silva AlmeidaNational Center of Nuclear Magnetic Resonance (CNRMN, CENABIO), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Marc A Sprague-PiercyDepartment of Molecular Biology and Biochemistry, University of California, Irvine, CA, United States.
Georgios A SpyrouliasDepartment of Pharmacy, University of Patras, Patras, Greece.
Sridhar SreeramuluInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Jan-Niklas TantsCenter of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Frankfurt am Main, Germany.
Kaspars TārsLatvian Biomedical Research and Study Centre, Riga, Latvia.
Felix TorresSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Sabrina TöwsInstitute for Molecular Biosciences, Goethe University Frankfurt, Frankfurt am Main, Germany.
Miguel Á Treviño"Rocasolano" Institute for Physical Chemistry (IQFR), Spanish National Research Council (CSIC), Madrid, Spain.
Sven TrucksInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Aikaterini C TsikaDepartment of Pharmacy, University of Patras, Patras, Greece.
Krisztina VargaDepartment of Molecular, Cellular, and Biomedical Sciences, University of New Hampshire, Durham, NH, United States.
Ying WangBMWZ and Institute of Organic Chemistry, Leibniz University Hannover, Hannover, Germany.
Marco E WeberSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Julia E WeigandDepartment of Biology, Technical University of Darmstadt, Darmstadt, Germany.
Christoph WiedemannInstitute of Biochemistry and Biotechnology, Charles Tanford Protein Centre, Martin Luther University Halle-Wittenberg, Halle/Saale, Germany.
Julia Wirmer-BartoschekInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Maria Alexandra Wirtz MartinInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Johannes ZehnderSwiss Federal Institute of Technology, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
Martin HengesbachInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Frankfurt am Main, Germany.
Andreas SchlundtCenter of Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt, Frankfurt am Main, Germany.
Goethe University Frankfurt · DEETH Zurich · CHUniversidade Federal do Rio de Janeiro · BRCentre National de la Recherche Scientifique · FRUniversity of California, Irvine · USInstitut de Biologie Structurale · FRUConn Health · USUniversity of New Hampshire · USUniversity of Patras · GRUniversity of Wisconsin–Madison · USCEA Grenoble · FRInteruniversity Consortium for Magnetic Resonance · ITKarlsruhe Institute of Technology · DELatvijas Organiskās Sintēzes Institūts · LVLeibniz Institute on Aging - Fritz Lipmann Institute (FLI) · DELeibniz University Hannover · DERi.MED · ITUniversité Claude Bernard Lyon 1 · FRConsejo Superior de Investigaciones Científicas · ESLatvian Biomedical Research and Study Centre · LV
Funding
Methods to accelerate protein structure determination by solution NMRZIADK029046 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI BAX, ADRIAAN · 2009 to 2025
$12.8MSolid-state NMR methods for investigating native and aggregated eye lens proteinsR01EY021514 · NEI · UNIVERSITY OF CALIFORNIA-IRVINE · PI MARTIN, RACHEL WAGNER · 2011 to 2022
$2.8MCoronavirus RNA synthesis by multicomponent protein machinesR01AI158463 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KIRCHDOERFER, ROBERT N · 2020 to 2025
$2.1MStructural Studies of the Corona Virus Life CycleR00AI123498 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KIRCHDOERFER, ROBERT N · 2020 to 2021
$719kNEI NIH HHS R01 EY021514NIAID NIH HHS R00 AI123498NIAID NIH HHS R01 AI158463
Abstract
The highly infectious disease COVID-19 caused by the
Indexed as
accessory proteinscell-free protein synthesisCOVID-19intrinsically disordered regionNMR spectroscopynonstructural proteinsSARS-CoV-2structural proteins
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