Evidence map›Paper›PMID 34041208›Full record

ArticleFrontiers in pediatrics2021

Resuscitation in Paediatric Sepsis Using Metabolic Resuscitation-A Randomized Controlled Pilot Study in the Paediatric Intensive Care Unit (RESPOND PICU): Study Protocol and Analysis Plan.

Luregn J Schlapbach, Kristen Gibbons, Roberta Ridolfi, Amanda Harley, Michele Cree, Debbie Long, David Buckley, Simon Erickson, Marino Festa, Shane George and 5 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06478797 (Adrenaline in Early Sepsis Resuscitation in Children- A Randomised Controlled Pilot Study in the Emergency Department), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06478797 phase2unknown statusnot on this mapstarted 2024, after this paper: background citation

Adrenaline in Early Sepsis Resuscitation in Children- A Randomised Controlled Pilot Study in the Emergency Department (ANDES CHILD)

TypeinterventionalSponsorNATALIA LOPERA MUNERARan2024 to 2025Enrolled40ConditionsSepsisArmsFluid, Adrenalin
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. The Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG): 20 Years of Collaborative Research.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025
    Article
  2. Serum Levels of Vitamin C and Thiamin in Children With Suspected Sepsis: A Prospective Observational Cohort Study.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2024
    Observational
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Luregn J SchlapbachChild Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia.
Kristen GibbonsChild Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia.
Roberta RidolfiChild Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia.
Amanda HarleyChild Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia.
Michele CreeChild Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia.
Debbie LongChild Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia.
David BuckleyPaediatric Intensive Care Unit, Starship Children's Hospital, Auckland, New Zealand.
Simon EricksonPaediatric Critical Care Unit, Perth Children's Hospital, Perth, WA, Australia.
Marino FestaPaediatric Intensive Care Unit, Children's Hospital Westmead, Sydney, NSW, Australia.
Shane GeorgeChild Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia.
Megan KingDepartments of Emergency Medicine and Children's Critical Care, Gold Coast University Hospital, Southport, QLD, Australia.
Puneet SinghPaediatric Intensive Care Unit, Sydney Children's Hospital, Sydney, NSW, Australia.
Sainath RamanChild Health Research Centre, The University of Queensland, and Paediatric Intensive Care Unit, Queensland Children's Hospital, Brisbane, QLD, Australia.
Rinaldo BellomoIntensive Care Research, Austin Hospital and Monash University, Melbourne, VIC, Australia.
RESPOND PICU study investigators and the Australian New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG)
University of Queensland · AUQueensland Children’s Hospital · AUAustin Hospital · AUGriffith University · AUPrincess Margaret Hospital for Children · AUStarship Children's Health · NZSydney Children's Hospital · AUSydney Children’s Hospitals Network · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ascorbic acidchildhydrocortisoneintensive caresepsisseptic shockthiaminevitamin C

Identifiers

PMID34041208
PMCPMC8142861
OpenAlexW3159246460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.