Evidence map›Paper›PMID 34041006›Full record

ArticleJournal of reproduction & infertility

Evaluation of Microdissection Testicular Sperm Extraction (mTESE), Outcomes and Predictive Factors in Ireland: The Gold Standard for Men with Non-Obstructive Azoospermia.

Pat Rohan, Niamh Daly, Aoife O'Kelly, Martin O'Leary, Tim Dineen, Nigam Shah, Padraig Daly, John Waterstone, Ivor Cullen

Open access · greenAbstract read
In one paragraph

Article in Journal of reproduction & infertility. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Fresh versus frozen micro-TESE sperm and outcomes.Asian journal of andrology · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Pat RohanDepartment of Urology, University Hospital Waterford, Waterford, Ireland.
Niamh DalyWaterstone Clinic, Cork, Ireland.
Aoife O'KellyDepartment of Urology, University Hospital Waterford, Waterford, Ireland.
Martin O'LearyCollege of Science, University College Dublin, Dublin, Ireland.
Tim DineenWaterstone Clinic, Cork, Ireland.
Nigam ShahDepartment of Pathology, University Hospital Waterford, Waterford, Ireland.
Padraig DalyDepartment of Urology, University Hospital Waterford, Waterford, Ireland.
John WaterstoneWaterstone Clinic, Cork, Ireland.
Ivor CullenDepartment of Urology, University Hospital Waterford, Waterford, Ireland.
University Hospital Waterford · IEUniversity College Dublin · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrodissection testicular sperm extraction (mTESE) is the gold standard approach in sperm retrieval in men with non-obstructive azoospermia (NOA). The purpose of the study was to assess the outcomes for Irish men who have undergone mTESE with a single surgeon.

methodsThis is a retrospective, single cohort study. Thirty-four patients underwent mTESE between September 2015 and June 2019. A p<0.05 was considered statistically significant.

resultsIn this study, sperm retrieval rate (SRR) was 47.06%. (16/34). The mean age in those who had retrieved sperm at mTESE was 37.9±2.6 years. Johnson Score (JS) and FSH were statistically different between successful and unsuccessful mTESE groups (p=0.017*10

conclusionThe combination of mTESE/Intracytoplasmic sperm injection (ICSI) is the best option available for men with NOA who prefer to achieve paternity using their own DNA. Given the overall SRRs in mTESE, it is imperative to continue research for a predictive model to better counsel azoospermic men regarding the use of mTESE. For this purpose, large, multicenter, randomized controlled trials are needed.

Indexed as

Male infertilityMicrodissection testicular sperm extractionNon-obstructive azoospermiaPredictive markersSperm retrieval

Identifiers

PMID34041006
PMCPMC8143015
OpenAlexW3139434791

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.