Evidence map›Paper›PMID 34040995›Full record

ArticleToxicology reports2021

Phthalates exposure during pregnancy a study in a Mexican cohort.

Lilia Patricia Bustamante-Montes, Víctor Hugo Borja-Aburto, María Hernández-Valero, María Magdalena García-Fábila, Patricia Borja-Bustamante, Rafael González-Álvarez, Germán Antonio Acosta-Gordillo

Open access · goldAbstract read
In one paragraph

Article in Toxicology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. A Children's Health Perspective on Nano- and Microplastics.Environmental health perspectives · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Lilia Patricia Bustamante-MontesUniversidad Autónoma de Guadalajara, Decanato de Ciencias de la Salud, Guadalajara, Jalisco, Mexico.
Víctor Hugo Borja-AburtoInstituto Mexicano del Seguro Social (IMSS), Coordinacion de Vigilancia Epidemiologica, Ciudad de Mexico, Mexico.
María Hernández-ValeroCollege of Acupuncture & Oriental Medicine, Houston, TX, USA.
María Magdalena García-FábilaUniversidad Autónoma del Estado de México, Facultad de Química, Toluca, Estado de México, Mexico.
Patricia Borja-BustamanteInstituto Mexicano del Seguro Social (IMSS), Coordinacion de Vigilancia Epidemiologica, Ciudad de Mexico, Mexico.
Rafael González-ÁlvarezUniversidad Autónoma de Guadalajara, Decanato de Ciencias de la Salud, Guadalajara, Jalisco, Mexico.
Germán Antonio Acosta-GordilloUniversidad Autónoma de Guadalajara, Decanato de Ciencias de la Salud, Guadalajara, Jalisco, Mexico.
Universidad Autónoma de Guadalajara · MXMexican Social Security Institute · MXAmerican College of Acupuncture & Oriental Medicine · USUniversidad Autónoma del Estado de México · MX

Funding

SHARED RESOUCES COREP60MD000503 · NIMHD · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI LI, YISHENG · 2003 to 2011
$12.4M
NIMHD NIH HHS P60 MD000503
6 · The paper itself

Abstract

A prospective cohort study was conducted to measure the concentration levels of three primary phthalate metabolites (MBP, MEHP, MEP) during pregnancy in a group of women from the State of Mexico. The urinary concentration levels of the three phthalate primary metabolites were measured by gas chromatography mass spectrometry during the first, second and third trimesters of pregnancy. The geometric mean and 95 % CI for MBP was 20.38 μg/mL (15.35-27.09); for MEHP 13.43 μg/mL (8.93-20.20), and MEP 52.47 μg/mL (39.88-69.04) adjusted to one g of creatinine. No significant trends were observed among the studied metabolites during the pregnancy period. MBP was higher in less educated women, while women who resided in industrialized zones showed higher levels of MEHP and MEP than women from non-industrialized zones. Consumption of plastic bottled beverages was associated with MBP and MEHP phthalate exposure. Women who used non-registered brands of plastic food containers for storage or for microwave oven use showed the highest levels of MBP and MEP phthalates. The pregnant women in our study were exposed to the three studied primary phthalate metabolites, and this could present a risk to their newborns. To better integrate public health policies, major exploration of potential exposure sources and effects at the regional level is required.

Indexed as

Exposure assessmentMono-butyl phthalate (MBP)Mono-ethyl-hexyl phthalate (MEHP)Mono-ethyl phthalate (MEP)Pregnancy

Identifiers

PMID34040995
PMCPMC8142082
OpenAlexW3163129977

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.