ArticleGlobal heart2021
Global Burden of Aortic Aneurysm and Attributable Risk Factors from 1990 to 2017.
Article in Global heart, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Blood lipids and the risk of aortic aneurysm: results from the UK Biobank study and a systematic review and meta-analysis of cohort studies.European journal of epidemiology · 2026Pooled it
- Integrative bioinformatics frameworks for abdominal aortic aneurysm using GWAS meta-analysis, biological network construction, and structural modeling.Scientific reports · 2025Pooled it
- Global, Regional, and National Burden of Aortic Aneurysm, 1990-2021, and Projections to 2050.Journal of Korean medical science · 2026Article
- Chemotherapy is associated with faster abdominal aortic aneurysm growth in patients with concomitant cancer in a multicenter cohort.Clinics (Sao Paulo, Brazil) · 2026Article
- Application of radiomics in abdominal aortic aneurysm and endovascular aneurysm repair-related adverse events imaging: a systematic review.CVIR endovascular · 2026Review
- The Global Burden of Aortic Aneurysm and Its Attributable Risk Factors, 1990-2021: Results from the Global Burden of Disease Study 2021.Health science reports · 2026Article
- Macrophage Gsα promotes NLRP3 stability and its intervention attenuates abdominal aortic aneurysm in male mice.Nature communications · 2026Article
- Evaluating the feasibility of robotic-assisted abdominal aortic replacement in a porcine model.Journal of robotic surgery · 2026Article
- HDL in Abdominal Aortic Aneurysm: Mechanistic Insight and Therapeutic Potential.Current atherosclerosis reports · 2026Review
- Burden of aortic aneurysm and lead exposure risk factor in adults aged 60 years and older from 1990 to 2021: a global, regional, and national analysis.Frontiers in public health · 2026Article
- Global burden of aortic aneurysm from high body mass index and systolic blood pressure in older adults: 1990-2021 and projections to 2050.Archives of medical science : AMS · 2026Article
- Delayed Diagnosis of a Giant Abdominal Aortic Aneurysm Complicating to Aortoenteric Fistula: A Case Report and Literature Review.Clinical case reports · 2026Article
- Circulating Protein Mediators Linking Genetically Predicted Smoking to Abdominal Aortic Aneurysm: A Genomic-Proteomic Analysis.Arteriosclerosis, thrombosis, and vascular biology · 2025Article
- Global, Regional, and National Burden of Aortic Aneurysm and Its Attributable Risk Factors from 1990 to 2021: An Analysis of the Global Burden of Disease Study 2021.Archives of Iranian medicine · 2025Article
- The Association Between Serum HMGB2 Levels and Abdominal Aortic Aneurysm in Males: Insights Into the HMGB2-TREM Pathway.Reviews in cardiovascular medicine · 2025Article
- Association of Estimated Glucose Disposal Rate With Risk of Abdominal Aortic Aneurysm: Evidence From a Large-Scale Prospective Cohort Study of the UK Biobank.Reviews in cardiovascular medicine · 2025Article
- Disease burden of aortic aneurysm from 1990 to 2021 with a forecast to 2045: insights from the global burden of disease 2021.BMC public health · 2025Article
- Causal relationship between serum metalloproteinase 12 levels and aortic dissection and aortic aneurysm: a bidirectional Mendelian randomization study.Journal of thoracic disease · 2025Article
- Investigating long-term risk of aortic aneurysm and dissection from fluoroquinolones and the key contributing factors using machine learning methods.Scientific reports · 2025Article
- Restoring Vascular Smooth Muscle Cell Mitochondrial Function Attenuates Abdominal Aortic Aneurysm in Mice.Arteriosclerosis, thrombosis, and vascular biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: To date, our understanding of the global aortic aneurysm (AA) burden distribution is very limited. Objective: To assess a full view of global AA burden distribution and attributable risk factors from 1990 to 2017. Methods: We extracted data of AA deaths, disability-adjusted life years (DALYs), and their corresponding age-standardized rates (ASRs), in general and by age/sex from the 2017 Global Burden of Disease (GBD) study. The current AA burden distribution in 2017 and its changing trend from 1990 to 2017 were separately showed. The spatial divergence was discussed from four levels: global, five social-demographic index regions, 21 GBD regions, and 195 countries and territories. We also estimated the risk factors attributable to AA related deaths. Results: Globally, the AA deaths were 167,249 with an age-standardized death rate (ASDR) of 2.19/100,000 persons in 2017, among which the elderly and the males accounted for the majority. Although reductions in ASRs were observed in developed areas, AA remained an important health issue in those relatively underdeveloped areas and might be much more important in the near future. AA may increasingly affect the elderly and the female population. Similar patterns of AA DALYs burden were noted during the study period. AA burden attributable to high blood pressure and smoking decreased globally and there were many heterogeneities in their distribution. Discussion: AA maintained an incremental public health issue worldwide. The change pattern of AA burden was heterogeneous across locations, ages, and sexes and it is paramount to improve resource allocation for more effective and targeted prevention strategies. Also, prevention of tobacco consumption and blood pressure control should be emphasized.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.