ArticleCureus2021
Dementia and Adherence to Anti-Diabetic Medications: A Meta-Analysis.
Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Prevalence, awareness, treatment, and control of prediabetes and diabetes mellitus in older adults: findings from Iranian STEPS surveys (2016 and 2021).BMC public health · 2025Article
- The Impact of Medication Regimen Adjustment Ratio on Adherence and Glycemic Control in Patients with Type 2 Diabetes and Mild Cognitive Impairment.Biomedicines · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction Diabetes mellitus (DM) and dementia (DN) are common morbid disorders with high mortality, the two disorders shared the pathogenesis of proinflammation and insulin resistance. Polypharmacy is expected when DM and DN co-exist and medication adherence is essential to an effective self-care and management plan. This meta-analysis aimed to assess medication persistence among patients with diabetes and cognitive impairment (CogImp). Methods We systematically searched the literature through PubMed, Medline, Cochrane library, and the first 100 articles published in Google Scholar. We included articles publishes in English and conducted on humans, no limitation was set to the date of publication, all the articles were approached from the first published up to March 15, 2021. The keywords used were Dementia, cognitive impairment, cognitive decline, cognitive dysfunction, diabetes self-care, compliance to anti-diabetic drugs, and medication adherence. One hundred-seventy-six were identified, the 12 full texts screened, only four fulfilled the inclusion and exclusion criteria. Results The studies were published in Europe, the United States, and Asia (all were observational). The results showed no effects of dementia on medication adherence, P-value of 0.41, odd ratio: 1.09, 95% CI: 0.89-1.32, Chi-square for heterogeneity: 12.15, I
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.